The article illustrates the pharmacoepidemiology of the use of antibacterial drugs on the example of cephalosporins, since irrational dosing, lowering the dose of antibacterial drugs below the doses specified in local and international guidelines and standards, and reducing the duration of treatment can cause of the development of microorganism resistance. Analyzing the doses and duration of the use of cephalosporins in chronic obstructive pulmonary disease (COPD), irrational use and incorrect dosing regimen of some cephalosporins (cefazolin, cefepime) were established, which are common mistakes in the use of antibiotics, and this in turn contributes to a decrease in their effectiveness and the development of microbial resistance to these drugs. A higher average duration of cefazolin use (7.8±2.3) compared to other cephalosporins indicates a decrease in the effectiveness of the drug and this may be due to irrational use and incorrect dosing of cefazolin.
| Mualliflar | SIDDIKOV Olim Abdullaevich, NURALIEVA Rano Matyakubovna, DAMINOVA Lola Turgunpulatovna |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2022-05-31 |
| Jild | 7 |
| Son | 2 |
| Til | Rus |
ХОБЛ, фармакоэпидемиология, цефалоспорины, цефазолин, оптимизация, антибактериальные препараты, COPD, pharmacoepidemiology, cephalosporins, cefazolin, optimization, antibacterial drugs., ЎСОК, фармакоэпидемиология, цефалоспоринлар, цефазолин, оптималлаштириш, антибактериал препаратлар
Given the complexity and versatility of the pathogenesis of type 2 diabetes, the choice of antihyperglycemic drugs is based on the importance of a simultaneous combined effect on several links in the pathogenesis of…
Objective: to determine the sensitivity of oral microbes in endodontic treatment both in the oral fluid and root canals. Methods: The study determined the sensitivity of microbes living in the oral cavity to sodium…
The aim of our work was to develop a comprehensive, pathogenetic substantiated intensive care in patients with diabetic ketoacidosis who are in critical condition. The development of complex pathogenetic substantiated…
Medicine at the present stage does not stand still, its progress leads to the concretization of methodological approaches. Currently, pharmacological science does not stand still, new medicines (drugs) are appearing and…
Objective: To assess the severity of nephropathy in diabetes mellitus according to laboratory parameters. Methods: The study was carried out on the basis of the Samarkand Regional General Hospital, Department of…
The article presents the results of the COLCORONA, KOLORIT, GRECCO-19 studies on the effectiveness of colchicine in the treatment of COVID-19.
The purpose of the study: to assess the structural and functional state of the liver in patients in the early rehabilitation period of COVID-19. Materials and research methods. Under observation were 243 patients who…
This article provides information on the chemical composition of melon seeds and skins, as well as their importance in traditional medicine.
In recent years, the strategy and tactics of surgical treatment of patients with multiple and combined injuries of the abdomen were marked by a change in the paradigm and a revision of the concept of total care (early…
The authors, in the experimental group of animals, to prevent complications of colon suture insufficiency (CSI), performed therapeutic manipulations in the form of sessions of laser exposure to the zone of the formed…
Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali — barcha maqolalar