Diabetic retinopathy (DR) is considered a microcirculatory disease of the retina. However, new data are emerging that suggest that retinal neurodegeneration is an early event in the pathogenesis of DR, which may precede the development of microcirculatory disorders that occur in DR, as well as participate in them. Therefore, studying the underlying mechanisms that lead to neurodegeneration will be essential for identifying new therapeutic targets in the early stages of DR. Elevated glutamate levels, oxidative stress, overexpression of the renin-angiotensin system, and activation of glycation end-product receptors play important roles in diabetic-induced retinal neurodegeneration. Finally, the balance between neurotoxic and neuroprotective factors is critical in determining the survival of retinal neurons. In this review, we focus on neurotrophic factors already synthesized by the retina under physiological conditions, and we also discuss current neuroprotective strategies and future directions for the treatment of DR.
| Mualliflar | Muji-Emiliya Komiljonovna Mustafaeva, Fazilat Arifovna Bahritdinova |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashriyot | Тошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ |
| ISSN | 2181-9300 |
| Nashr sanasi | 2021-02-26 |
| Jild | 6 |
| Son | 1 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-27 |
Диабетическая ретинопатия. Нейродегенерация. Нейропротекция. Лечение диабетической ретинопатии. Нервно-сосудистая связь, Diabetic retinopathy. Neurodegeneration. Neuroprotection. Diabetic retinopathy treatment. Neurovascular connection, Diabetik retinopatiya. Neyrodejeneratsiya. Neyroprotektsiya. Diyabetik retinopatiyani davolash. Neyrovaskulyar birikma
| APA | Muji-Emiliya Komiljonovna Mustafaeva, & Fazilat Arifovna Bahritdinova (2021). NEUROPROTECTION AS A THERAPEUTIC TARGET IN DIABETIC RETINOPATHY. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 6(1). https://tadqiqot.uz/index.php/biomedicine/article/view/201 |
|---|---|
| GOST (OAK) | Muji-Emiliya Komiljonovna Mustafaeva, Fazilat Arifovna Bahritdinova NEUROPROTECTION AS A THERAPEUTIC TARGET IN DIABETIC RETINOPATHY // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2021. – T. 6, № 1. |
| MLA | Muji-Emiliya Komiljonovna Mustafaeva, and Fazilat Arifovna Bahritdinova. “NEUROPROTECTION AS A THERAPEUTIC TARGET IN DIABETIC RETINOPATHY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 6(1), 2021. https://tadqiqot.uz/index.php/biomedicine/article/view/201 |
| Chicago | Muji-Emiliya Komiljonovna Mustafaeva, and Fazilat Arifovna Bahritdinova. “NEUROPROTECTION AS A THERAPEUTIC TARGET IN DIABETIC RETINOPATHY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 6(1) (2021). https://tadqiqot.uz/index.php/biomedicine/article/view/201 |
| Harvard | Muji-Emiliya Komiljonovna Mustafaeva, and Fazilat Arifovna Bahritdinova (2021) ‘NEUROPROTECTION AS A THERAPEUTIC TARGET IN DIABETIC RETINOPATHY’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 6(1). https://tadqiqot.uz/index.php/biomedicine/article/view/201 |
| BibTeX | @article{mujiemiliyakomiljonovnamustafaeva2021,
title = {NEUROPROTECTION AS A THERAPEUTIC TARGET IN DIABETIC RETINOPATHY},
author = {Muji-Emiliya Komiljonovna Mustafaeva and Fazilat Arifovna Bahritdinova},
journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
year = {2021},
volume = {6},
number = {1},
url = {https://tadqiqot.uz/index.php/biomedicine/article/view/201}
} |
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