Morphological manifestations of myocardial lesion in COVID-19

Zumrad , Rajabboy, Ergasheva, Zumrad, Исраилов , Ражаббой, Эргашева, Зумрад, Zumrad , Rajabboy, Ergasheva, Zumrad

Халқаро илмий педиатрия журнали · 2022-yil

Annotatsiya

To date, the pathogenesis and morphogenesis of COVID-19 have not been studied in depth, and therefore, in this work, the goal is to study the damage to the parenchymal-stromal elements of the myocardium in COVID-19. The material for the study was pieces from the myocardium of the ventricular wall of 26 patients who died from COVID-19 at the age of 28 to 56 years. The results of a morphological study showed that edema and mucoid swelling of the interstitial tissue of the myocardium in COVID-19 occurs due to the accumulation of hyaluronan, the development of dystrophy, dysregeneration and inflammation of blood vessels and connective tissue structures. In the myocardial parenchyma, contracture disorders, homogeneous compaction of the cytoplasm of cardiomyocytes, disappearance of the transverse striation of myofibrils, focal development of basophilia, PAS-positive metaplasia of cardiomyocytes, fragmentation, degeneration and necrobiosis of muscle fibers were noted; compaction, deformation and destruction of the nuclei of cardiomyocytes. Injuries to cardiomyocytes are first manifested by sarcoplasm vacuolization, a change in the coloration and shape of the nucleus, then enlargement and hyperchromasia of the nucleus in the form of dysplasia occur, homogenization, metachromasia and blue staining are noted from the sarcoplasm, followed by lysis of the nucleus; in the future, metachromasia covers the entire cytoplasm of the cardiomyocyte and the cell dies.

Maqola ma’lumotlari
MualliflarZumrad , Rajabboy, Ergasheva, Zumrad, Исраилов , Ражаббой, Эргашева, Зумрад, Zumrad , Rajabboy, Ergasheva, Zumrad
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2022-05-31
Jild1
Son1
Betlar46-52
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2022-1-46-52
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-2926-2022-1-46-52 · Maqolaning asl sahifasi

Kalit so‘zlar

COVID-19, Сердце, Миокард, Кардиомиоциты, Интерстиций, Дистрофия, Воспаление, Дисрегенерация, COVID-19, Heart, Myocardium, Cardiomyocytes, Interstitium, Dystrophy, Inflammation, Dysregeneration, COVID-19, Yurak, Miokard, Kardiomiotsit, Interstitsiya, Distrofiya, Yallig’lanish, Disregeneratsiya

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAZumrad , Rajabboy, Ergasheva, Zumrad, Исраилов , Ражаббой, Эргашева, Зумрад, Zumrad , Rajabboy, & Ergasheva, Zumrad (2022). MORPHOLOGICAL MANIFESTATIONS OF MYOCARDIAL LESION IN COVID-19. Халқаро илмий педиатрия журнали, 1(1), 46-52. https://doi.org/10.56121/2181-2926-2022-1-46-52
GOST (OAK)Zumrad , Rajabboy va b. MORPHOLOGICAL MANIFESTATIONS OF MYOCARDIAL LESION IN COVID-19 // Халқаро илмий педиатрия журнали. – 2022. – T. 1, № 1. – P. 46-52. – DOI: 10.56121/2181-2926-2022-1-46-52.
MLAZumrad , Rajabboy, Ergasheva, Zumrad, Исраилов , Ражаббой, Эргашева, Зумрад, Zumrad , Rajabboy, and Ergasheva, Zumrad. “MORPHOLOGICAL MANIFESTATIONS OF MYOCARDIAL LESION IN COVID-19.” Халқаро илмий педиатрия журнали, 1(1), 46-52, 2022. https://doi.org/10.56121/2181-2926-2022-1-46-52
ChicagoZumrad , Rajabboy, Ergasheva, Zumrad, Исраилов , Ражаббой, Эргашева, Зумрад, Zumrad , Rajabboy, and Ergasheva, Zumrad. “MORPHOLOGICAL MANIFESTATIONS OF MYOCARDIAL LESION IN COVID-19.” Халқаро илмий педиатрия журнали, 1(1), 46-52 (2022). https://doi.org/10.56121/2181-2926-2022-1-46-52
HarvardZumrad , Rajabboy, Ergasheva, Zumrad, Исраилов , Ражаббой, Эргашева, Зумрад, Zumrad , Rajabboy, and Ergasheva, Zumrad (2022) ‘MORPHOLOGICAL MANIFESTATIONS OF MYOCARDIAL LESION IN COVID-19’, Халқаро илмий педиатрия журнали, 1(1), 46-52. https://doi.org/10.56121/2181-2926-2022-1-46-52
BibTeX
@article{zumradrajabboy2022,
  title = {MORPHOLOGICAL MANIFESTATIONS OF MYOCARDIAL LESION IN COVID-19},
  author = {Zumrad , Rajabboy and Ergasheva, Zumrad and Исраилов , Ражаббой and Эргашева, Зумрад and Zumrad , Rajabboy and Ergasheva, Zumrad},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2022},
  volume = {1},
  number = {1},
  pages = {46-52},
  doi = {10.56121/2181-2926-2022-1-46-52},
  url = {https://doi.org/10.56121/2181-2926-2022-1-46-52}
}

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