Studying the pharmacokinetics of gentamycin in rats with lymphotropic pretracheal and intramuscular introduction

Mamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, Ataxanova, Nilufar, Маматов, Бахтияржон, Муминов, Бахром, Кузиев, Озодбек, Абдуллаев, Азизбек, Собиров, Мухаммаджон, Исмоилов, Ойбек, Эргашев, Хуршидбек, Хасанов, Шокирхон, Атаханова, Нилуфар, Mamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, Ataxanova, Nilufar

Халқаро илмий педиатрия журнали · 2022-yil

Annotatsiya

The article is devoted to an experimental study of the pharmacokinetics of gentamicin in rats with lymphotropic pretracheal and intramuscular routes of administration. Data on the concentration of the antibiotic in the blood and tissues of the respiratory organs of rats in dynamics are given, it is shown that the method of lymphotropic pretracheal administration provides higher concentrations of the antibiotic in comparison with the intramuscular method. The high therapeutic efficiency of this method can be achieved due to the presence of connections between the lymphatic system, as well as organs and tissues. This circumstance allows you to deliver the drug to the affected organ directly. In addition, in the case of lymphotropic therapy in the focus, the optimal concentration of the drug is maintained for 24 hours. So there is no need for frequent administration of the drug (for example, with antibiotic therapy), you can reduce the course and daily doses of drugs. The drug, which is administered lymphotropically, is not able to have a toxic effect on the intestines, kidneys, liver, since only a tiny part of the drug enters the bloodstream.

Maqola ma’lumotlari
MualliflarMamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, Ataxanova, Nilufar, Маматов, Бахтияржон, Муминов, Бахром, Кузиев, Озодбек, Абдуллаев, Азизбек, Собиров, Мухаммаджон, Исмоилов, Ойбек, Эргашев, Хуршидбек, Хасанов, Шокирхон, Атаханова, Нилуфар, Mamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, Ataxanova, Nilufar
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2022-05-31
Jild1
Son1
Betlar30-40
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2022-1-30-40
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-2926-2022-1-30-40 · Maqolaning asl sahifasi

Kalit so‘zlar

Гентамицин, Метод Лимфотропного Претрахеального Введения, Внутримышечное Введение, Оптимальная Концентрация, Gentamicin, Method of Lymphotropic Pretracheal Administration, Intramuscular Administration, Concentration, Focus, Optimal Concentration, Gentamitsin, Limfotrop Pretrakeal Yuborish Usuli, Mushak Ichiga Yuborish, Konsentratsiya, Diqqat, Optimal Konsentratsiya

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAMamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, Ataxanova, Nilufar, Маматов, Бахтияржон, Муминов, Бахром, Кузиев, Озодбек, Абдуллаев, Азизбек, Собиров, Мухаммаджон, Исмоилов, Ойбек, Эргашев, Хуршидбек, Хасанов, Шокирхон, Атаханова, Нилуфар, Mamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, & Ataxanova, Nilufar (2022). STUDYING THE PHARMACOKINETICS OF GENTAMYCIN IN RATS WITH LYMPHOTROPIC PRETRACHEAL AND INTRAMUSCULAR INTRODUCTION. Халқаро илмий педиатрия журнали, 1(1), 30-40. https://doi.org/10.56121/2181-2926-2022-1-30-40
GOST (OAK)Mamatov, Baxtiyor va b. STUDYING THE PHARMACOKINETICS OF GENTAMYCIN IN RATS WITH LYMPHOTROPIC PRETRACHEAL AND INTRAMUSCULAR INTRODUCTION // Халқаро илмий педиатрия журнали. – 2022. – T. 1, № 1. – P. 30-40. – DOI: 10.56121/2181-2926-2022-1-30-40.
MLAMamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, Ataxanova, Nilufar, Маматов, Бахтияржон, Муминов, Бахром, Кузиев, Озодбек, Абдуллаев, Азизбек, Собиров, Мухаммаджон, Исмоилов, Ойбек, Эргашев, Хуршидбек, Хасанов, Шокирхон, Атаханова, Нилуфар, Mamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, and Ataxanova, Nilufar. “STUDYING THE PHARMACOKINETICS OF GENTAMYCIN IN RATS WITH LYMPHOTROPIC PRETRACHEAL AND INTRAMUSCULAR INTRODUCTION.” Халқаро илмий педиатрия журнали, 1(1), 30-40, 2022. https://doi.org/10.56121/2181-2926-2022-1-30-40
ChicagoMamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, Ataxanova, Nilufar, Маматов, Бахтияржон, Муминов, Бахром, Кузиев, Озодбек, Абдуллаев, Азизбек, Собиров, Мухаммаджон, Исмоилов, Ойбек, Эргашев, Хуршидбек, Хасанов, Шокирхон, Атаханова, Нилуфар, Mamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, and Ataxanova, Nilufar. “STUDYING THE PHARMACOKINETICS OF GENTAMYCIN IN RATS WITH LYMPHOTROPIC PRETRACHEAL AND INTRAMUSCULAR INTRODUCTION.” Халқаро илмий педиатрия журнали, 1(1), 30-40 (2022). https://doi.org/10.56121/2181-2926-2022-1-30-40
HarvardMamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, Ataxanova, Nilufar, Маматов, Бахтияржон, Муминов, Бахром, Кузиев, Озодбек, Абдуллаев, Азизбек, Собиров, Мухаммаджон, Исмоилов, Ойбек, Эргашев, Хуршидбек, Хасанов, Шокирхон, Атаханова, Нилуфар, Mamatov, Baxtiyor, Muminov, Baxrom, Qo'ziyev, Ozodbek, Abdullayev, Azizbek, Sobirov, Muxammadjon, Ismoilov, Oybek, Ergashev , Xurshidbek, Xasanov, Shokirxon, and Ataxanova, Nilufar (2022) ‘STUDYING THE PHARMACOKINETICS OF GENTAMYCIN IN RATS WITH LYMPHOTROPIC PRETRACHEAL AND INTRAMUSCULAR INTRODUCTION’, Халқаро илмий педиатрия журнали, 1(1), 30-40. https://doi.org/10.56121/2181-2926-2022-1-30-40
BibTeX
@article{mamatovbaxtiyor2022,
  title = {STUDYING THE PHARMACOKINETICS OF GENTAMYCIN IN RATS WITH LYMPHOTROPIC PRETRACHEAL AND INTRAMUSCULAR INTRODUCTION},
  author = {Mamatov, Baxtiyor and Muminov, Baxrom and Qo'ziyev, Ozodbek and Abdullayev, Azizbek and Sobirov, Muxammadjon and Ismoilov, Oybek and Ergashev , Xurshidbek and Xasanov, Shokirxon and Ataxanova, Nilufar and Маматов, Бахтияржон and Муминов, Бахром and Кузиев, Озодбек and Абдуллаев, Азизбек and Собиров, Мухаммаджон and Исмоилов, Ойбек and Эргашев, Хуршидбек and Хасанов, Шокирхон and Атаханова, Нилуфар and Mamatov, Baxtiyor and Muminov, Baxrom and Qo'ziyev, Ozodbek and Abdullayev, Azizbek and Sobirov, Muxammadjon and Ismoilov, Oybek and Ergashev , Xurshidbek and Xasanov, Shokirxon and Ataxanova, Nilufar},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2022},
  volume = {1},
  number = {1},
  pages = {30-40},
  doi = {10.56121/2181-2926-2022-1-30-40},
  url = {https://doi.org/10.56121/2181-2926-2022-1-30-40}
}

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