Pathomorphological evaluation of the antituberculosis efficacy of Rifizostrep in experimental calf tuberculosis

MAMADULLAEV, G. Kh., DJURAEV, O. A., DJURAKULOV, O. K., МАМАДУЛЛАЕВ, Г.Х., ДЖУРАЕВ, О.А., ДЖУРАКУЛОВ, О.К., MAMADULLAEV, G.H., DJURAEV, O.A., DJURAQULOV, O.Q.

Research Focus · 2026-yil

Annotatsiya

This study presents the results of pathomorphological and histomorphological investigations of the internal organs of experimental calves used in studies of the efficacy of the Rifizostrep preparation. A novel combination anti-tuberculosis drug, Rifizostrep, was developed by researchers at the Scientific-Research Institute of Veterinary. Administration of this preparation to animals demonstrated its sufficiently effective bactericidal activity against M. tuberculosis in experimental tuberculosis. Concurrently, it was found that Rifizostrep exerts no adverse or detrimental effects on the organism as a whole or on the structure of the internal organs of the experimental calves. Analysis indicated that prolonged administration of the preparation resulted in minor structural changes, characterized by haemosiderosis in the cellular structure of the parenchymal organs and a slight increase in gastrointestinal secretion. Based on the findings of pathomorphological and laboratory histological examinations, the preparation was established to be harmless to the animal organism and to exert no general or acute toxic effects.

Maqola ma’lumotlari
MualliflarMAMADULLAEV, G. Kh., DJURAEV, O. A., DJURAKULOV, O. K., МАМАДУЛЛАЕВ, Г.Х., ДЖУРАЕВ, О.А., ДЖУРАКУЛОВ, О.К., MAMADULLAEV, G.H., DJURAEV, O.A., DJURAQULOV, O.Q.
JurnalResearch Focus
NashriyotВетеринария ИТИ ва “Илм-фан ва инновациялар академияси” МЧЖ
ISSN2181-3833
Nashr sanasi2026-08-05
Jild5
Son7
Betlar39-44
TilIngliz
Ilmiy sohaVeterinariya
DOI10.66073/refocus.v5i7.0706
Indeksga qo‘shilgan2026-09-07

DOI: 10.66073/refocus.v5i7.0706 · Maqolaning asl sahifasi

Kalit so‘zlar

mycobacteria, tuberculosis, combination, preparation, Rifizostrep, dose, parenchymal organs, pathoanatomical, histomorphological, structure, haemosiderosis, in vivo, allergy, tuberculin, mikobakteriya, tuberkulyoz, kombinatsiya, preparat, Rifizostrep, doza, parenximatoz a’zolar, patologoanatomik, gistomorfologik, struktura, gemosideroz, in vivo, allergiya, tuberkulin, микобактерии, туберкулёз, комбинация, препарат, Рифизостреп, доза, паренхиматозные органы, патологоанатомический, гистоморфологический, структура, гемосидероз, in vivo, аллергия, туберкулин

Ilmiy soha

Veterinariya

Iqtibos keltirish

APAMAMADULLAEV, G. Kh., DJURAEV, O. A., DJURAKULOV, O. K., МАМАДУЛЛАЕВ, Г.Х., ДЖУРАЕВ, О.А., ДЖУРАКУЛОВ, О.К., MAMADULLAEV, G.H., DJURAEV, O.A., & DJURAQULOV, O.Q. (2026). Pathomorphological evaluation of the antituberculosis efficacy of Rifizostrep in experimental calf tuberculosis. Research Focus, 5(7), 39-44. https://doi.org/10.66073/refocus.v5i7.0706
GOST (OAK)MAMADULLAEV, G. Kh. va b. Pathomorphological evaluation of the antituberculosis efficacy of Rifizostrep in experimental calf tuberculosis // Research Focus. – 2026. – T. 5, № 7. – P. 39-44. – DOI: 10.66073/refocus.v5i7.0706.
MLAMAMADULLAEV, G. Kh., DJURAEV, O. A., DJURAKULOV, O. K., МАМАДУЛЛАЕВ, Г.Х., ДЖУРАЕВ, О.А., ДЖУРАКУЛОВ, О.К., MAMADULLAEV, G.H., DJURAEV, O.A., and DJURAQULOV, O.Q. “Pathomorphological evaluation of the antituberculosis efficacy of Rifizostrep in experimental calf tuberculosis.” Research Focus, 5(7), 39-44, 2026. https://doi.org/10.66073/refocus.v5i7.0706
ChicagoMAMADULLAEV, G. Kh., DJURAEV, O. A., DJURAKULOV, O. K., МАМАДУЛЛАЕВ, Г.Х., ДЖУРАЕВ, О.А., ДЖУРАКУЛОВ, О.К., MAMADULLAEV, G.H., DJURAEV, O.A., and DJURAQULOV, O.Q. “Pathomorphological evaluation of the antituberculosis efficacy of Rifizostrep in experimental calf tuberculosis.” Research Focus, 5(7), 39-44 (2026). https://doi.org/10.66073/refocus.v5i7.0706
HarvardMAMADULLAEV, G. Kh., DJURAEV, O. A., DJURAKULOV, O. K., МАМАДУЛЛАЕВ, Г.Х., ДЖУРАЕВ, О.А., ДЖУРАКУЛОВ, О.К., MAMADULLAEV, G.H., DJURAEV, O.A., and DJURAQULOV, O.Q (2026) ‘Pathomorphological evaluation of the antituberculosis efficacy of Rifizostrep in experimental calf tuberculosis’, Research Focus, 5(7), 39-44. https://doi.org/10.66073/refocus.v5i7.0706
BibTeX
@article{mamadullaevgkh2026,
  title = {Pathomorphological evaluation of the antituberculosis efficacy of Rifizostrep in experimental calf tuberculosis},
  author = {MAMADULLAEV, G. Kh. and DJURAEV, O. A. and DJURAKULOV, O. K. and МАМАДУЛЛАЕВ, Г.Х. and ДЖУРАЕВ, О.А. and ДЖУРАКУЛОВ, О.К. and MAMADULLAEV, G.H. and DJURAEV, O.A. and DJURAQULOV, O.Q.},
  journal = {Research Focus},
  year = {2026},
  volume = {5},
  number = {7},
  pages = {39-44},
  doi = {10.66073/refocus.v5i7.0706},
  url = {https://doi.org/10.66073/refocus.v5i7.0706}
}

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