In this study, a biocomposite hydrogel was synthesized based on purified sodium carboxymethylcellulose (Na-CMC) with a degree of substitution (DS) of 0.88 and a degree of polymerization (DP) of 850, together with sericin obtained from natural silk. The physicochemical properties of the obtained hydrogel were investigated: electrostatic interactions between the carboxyl (–COO⁻) groups of Na-CMC and the amide I and amide II groups of sericin macromolecules were identified in the FTIR spectrum within the range of 1600-1700 cm⁻¹. Rheological studies confirmed that intermolecular crosslinking between the functional groups of Na-CMC and sericin led to a proportional increase in the viscosity of the hydrogel. After lyophilization of the Na-CMC/sericin hydrogel, scanning electron microscopy (SEM) revealed a porous structure with pore sizes ranging from 20 to 110 μm. The synthesized Na-CMC/sericin biocomposites hydrogel containing stable Ag–Bi bimetallic nanoparticles with sizes of 5–160 nm demonstrate strong potential for application in medical practice as non-surgical therapeutic biomaterials for the treatment of gastric and duodenal ulcer disease.
| Jurnal | O'ZBEKISTON POLIMERLAR JURNALI |
|---|---|
| Nashr sanasi | 2026-07-02 |
| Betlar | 19-19 |
| DOI | 10.66640/ujp-2026-5-00008 |
DOI: 10.66640/ujp-2026-5-00008 · Maqolaning asl sahifasi
This article presents the optimization of sulfur-cellulose composite (SCC) synthesis via inverse vulcanization using waste elemental sulfur (𝑆8 ) and activated cotton husk. A three‑factor Box-Behnken design was applied…
The use of potassium permanganate (KMnO₄) as an oxidizing agent provides a relatively straightforward yet effective route for tailoring the structure of cellulose under acidic conditions. In this work, microcrystalline…
In this study, the formation of silver nanoparticles (AgNPs) within a graft copolymer matrix based on dialdehyde carboxymethyl cellulose (DCMC) and silk sericin was investigated. The formation of Schiff bases between…
Hydrogels have emerged as indispensable biomaterials in tissue engineering and organoid technology due to their structural similarity to the native extracellular matrix (ECM), tunable mechanical properties, and…
This study presents an electrochemical impedance spectroscopy (EIS) analysis of proton exchange nanocomposite membranes (NDK) in compari-son with commercial Nafion 117 under fully hydrated conditions. The im-pedance…
The origin of the problem is associated with the expansion of application areas of ion-exchange resins used on an industrial scale. The aim of the research is to obtain polyampholytes with new sorption properties…
Dissolving polymer microneedles based on hydroxypropyl methylcellulose (HPMC), sodium carboxymethylcellulose (Na-CMC), polyvinyl alcohol (PVA), and their binary hydrogel blends were fabricated using a micromolding…
This study focuses on the synthesis and characterization of Ti3C2Tx, a prominent member of the MXene family known for its unique structural properties. MXene was synthesized using the selective etching of aluminum from…
A rationally engineered ternary phosphide electrocatalyst CoFeNi-P/NF was developed through hydrothermal growth followed by controlled vapor-phase phosphorization to address the kinetic limitations of alkaline water…
This study focuses on the synthesis and characterization of Ti3C2Tₓ, a prominent member of the MXene family known for its unique structural properties. MXene was synthesized using the selective etching of aluminum from…