The purpose of this research was to study Quanadex as an adjuvant to Longocain Heavy 0.5% solution for injections for clinical and physiological characteristics, efficacy and neonatal outcomes during cesarean section. A prospective double-blind randomized controlled clinical trial was conducted in 189 women, without severe extragenital pathology, with ASA II physical status. Group I consisted of pregnant women who were intrathecally injected with Longocain Heavy 0.5% hyperbaric solution, Group II women were injected with Longocain Heavy 0.5% hyperbaric solution in combination with 6 mcg Quanadex. The intravenous infusion of balanced polyelectrolyte hyperosmolar solution of Reosorbilact in a volume of 3–5 ml/kg preceded the spinal injection. Central hemodynamics, ANS, interleukin-6 were assessed, and newborns were evaluated on the Apgar scale at the 1st and 5th minutes. Studies have shown that the use of Quanadex, a highly selective α2-adrenergic receptor agonist, as an adjuvant to a 0.5% solution of Longocaine Heavy accelerates the onset of sensory-motor blockade, provides a longer sensory-motor block without significant effect on hemodynamics and ANS parameters, significantly reduces anesthetic and surgical stress and does not have a depressive effect on newborns in neonatal period of adaptation.
| Mualliflar | Куличкин Юрий Всеволодович, Ким Ен – Дин, Ильхамов Акмаль Фаикович, Камилов Азиз Исраилович, Джураев Фарход Салахиддинович, Хайдаров Фахритдин Шухратович |
|---|---|
| Jurnal | Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) |
| Nashriyot | Самарқанд давлат тиббиёт университети |
| ISSN | 2017-2021 |
| Nashr sanasi | 2023-09-21 |
| Jild | 4 |
| Son | 3 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-26 |
Спинальная анестезия, кесарево сечение, кванадекс, α2 – адренорецептор, лонгокаин хеви, сенсорно – моторный блок, Quanadex, Longocaine Heavy, spinal anesthesia, Reosorbilact, interleukin-6, central hemodynamics, α2-adrenoreceptor, Kvanadeks, Longokain Xevi, spinal anesteziya, Reosorbilakt, interleykin-6, markaziy gemodinamika, α2-adrenoretseptor
| APA | Куличкин Юрий Всеволодович, Ким Ен – Дин, Ильхамов Акмаль Фаикович, Камилов Азиз Исраилович, Джураев Фарход Салахиддинович, & Хайдаров Фахритдин Шухратович (2023). CLINICAL AND PHYSIOLOGICAL CHARACTERISTICS OF SPINAL ANESTHESIA WITH QUANADEX DURING CESAREAN SECTION. Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3). https://tadqiqot.uz/index.php/uro/article/view/7977 |
|---|---|
| GOST (OAK) | Куличкин Юрий Всеволодович va b. CLINICAL AND PHYSIOLOGICAL CHARACTERISTICS OF SPINAL ANESTHESIA WITH QUANADEX DURING CESAREAN SECTION // Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали). – 2023. – T. 4, № 3. |
| MLA | Куличкин Юрий Всеволодович, Ким Ен – Дин, Ильхамов Акмаль Фаикович, Камилов Азиз Исраилович, Джураев Фарход Салахиддинович, and Хайдаров Фахритдин Шухратович. “CLINICAL AND PHYSIOLOGICAL CHARACTERISTICS OF SPINAL ANESTHESIA WITH QUANADEX DURING CESAREAN SECTION.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3), 2023. https://tadqiqot.uz/index.php/uro/article/view/7977 |
| Chicago | Куличкин Юрий Всеволодович, Ким Ен – Дин, Ильхамов Акмаль Фаикович, Камилов Азиз Исраилович, Джураев Фарход Салахиддинович, and Хайдаров Фахритдин Шухратович. “CLINICAL AND PHYSIOLOGICAL CHARACTERISTICS OF SPINAL ANESTHESIA WITH QUANADEX DURING CESAREAN SECTION.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3) (2023). https://tadqiqot.uz/index.php/uro/article/view/7977 |
| Harvard | Куличкин Юрий Всеволодович, Ким Ен – Дин, Ильхамов Акмаль Фаикович, Камилов Азиз Исраилович, Джураев Фарход Салахиддинович, and Хайдаров Фахритдин Шухратович (2023) ‘CLINICAL AND PHYSIOLOGICAL CHARACTERISTICS OF SPINAL ANESTHESIA WITH QUANADEX DURING CESAREAN SECTION’, Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3). https://tadqiqot.uz/index.php/uro/article/view/7977 |
| BibTeX | @article{article2023,
title = {CLINICAL AND PHYSIOLOGICAL CHARACTERISTICS OF SPINAL ANESTHESIA WITH QUANADEX DURING CESAREAN SECTION},
author = {Куличкин Юрий Всеволодович and Ким Ен – Дин and Ильхамов Акмаль Фаикович and Камилов Азиз Исраилович and Джураев Фарход Салахиддинович and Хайдаров Фахритдин Шухратович},
journal = {Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)},
year = {2023},
volume = {4},
number = {3},
url = {https://tadqiqot.uz/index.php/uro/article/view/7977}
} |
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