Study of the role of intraovarial factors in the regulation of steroidogenesis in polycystic ovary syndrome

Азизова Гуззал Джамбуловна, Асатова Мунира Мирюсуповна

Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2023-yil

Annotatsiya

The study involved 215 women aged 18 to 35 years (the average age was 25.8±3.28 years) with PCOS, who were included in the main group and 30 absolutely healthy women of the same age in the control group. The results of the studies conducted to study the nature of correlations, we revealed a significantly direct positive correlation between the indicators of inhibin B (r=0.74; p˂0.05), AMH(r=0.79; p˂0.05), IGF-I (r=0.67;p˂0.05), insulin (r=0.62; p˂0,05), the HOMA-IR (r=0.66; p˂0,05) and the LH level in patients with PCOS, while a negative inverse correlation was established between the levels of INH-B (r=-0.7;p˂0,05), AMH(r=-0.73; p˂0,05), IGF-I (r=-0.69; p˂0.05), insulin (r=-0.62; p˂0.05), HOMA-IR (r=-0.67; p˂0.05) and FSH level. From the above, it follows that an increased level of LH, often found in this disease, can increase the production of inhibin B, AMH, and IGFR-I by the cells in polycystic ovaries and increase the production of androgens, as a result of which, apparently, has a general negative effect on normal folliculogenesis and ovulation, which suggests that the pathogenesis PCOS may include interrelated disorders of the systems of some intra-ovarian factors and ovarian steroidogenesis.

Maqola ma’lumotlari
MualliflarАзизова Гуззал Джамбуловна, Асатова Мунира Мирюсуповна
JurnalJournal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)
NashriyotСамарқанд давлат тиббиёт университети
ISSN2017-2021
Nashr sanasi2023-09-21
Jild4
Son3
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

поликистоз яичников, бесплодие, гиперандрогения, нарушение менструальной функции, polycystic ovaries, infertility, hyperandrogenism, menstrual function disorder, polikistik tuxumdonlar, bepushtlik, giperandrogenizm, hayz koʼrish disfunktsiyasi.

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAАзизова Гуззал Джамбуловна, & Асатова Мунира Мирюсуповна (2023). STUDY OF THE ROLE OF INTRAOVARIAL FACTORS IN THE REGULATION OF STEROIDOGENESIS IN POLYCYSTIC OVARY SYNDROME. Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3). https://tadqiqot.uz/index.php/uro/article/view/7956
GOST (OAK)Азизова Гуззал Джамбуловна, Асатова Мунира Мирюсуповна STUDY OF THE ROLE OF INTRAOVARIAL FACTORS IN THE REGULATION OF STEROIDOGENESIS IN POLYCYSTIC OVARY SYNDROME // Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали). – 2023. – T. 4, № 3.
MLAАзизова Гуззал Джамбуловна, and Асатова Мунира Мирюсуповна. “STUDY OF THE ROLE OF INTRAOVARIAL FACTORS IN THE REGULATION OF STEROIDOGENESIS IN POLYCYSTIC OVARY SYNDROME.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3), 2023. https://tadqiqot.uz/index.php/uro/article/view/7956
ChicagoАзизова Гуззал Джамбуловна, and Асатова Мунира Мирюсуповна. “STUDY OF THE ROLE OF INTRAOVARIAL FACTORS IN THE REGULATION OF STEROIDOGENESIS IN POLYCYSTIC OVARY SYNDROME.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3) (2023). https://tadqiqot.uz/index.php/uro/article/view/7956
HarvardАзизова Гуззал Джамбуловна, and Асатова Мунира Мирюсуповна (2023) ‘STUDY OF THE ROLE OF INTRAOVARIAL FACTORS IN THE REGULATION OF STEROIDOGENESIS IN POLYCYSTIC OVARY SYNDROME’, Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(3). https://tadqiqot.uz/index.php/uro/article/view/7956
BibTeX
@article{article2023,
  title = {STUDY OF THE ROLE OF INTRAOVARIAL FACTORS IN THE REGULATION OF STEROIDOGENESIS IN POLYCYSTIC OVARY SYNDROME},
  author = {Азизова Гуззал Джамбуловна and Асатова Мунира Мирюсуповна},
  journal = {Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)},
  year = {2023},
  volume = {4},
  number = {3},
  url = {https://tadqiqot.uz/index.php/uro/article/view/7956}
}

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