Prevalence of A2 and A2B subgroups and anti-A1 antibody in blood donors at tertiary care center in Bangladesh: A cross sectional study

Tamanna Afroz, Abu Jafar Mohammed Saleh

PULSE · 2024-yil

Annotatsiya

Context: A2 and A2B are rare phenotypes of ABO blood group system. The presence of anti-A1 in A2 and A2B subgroups may cause hemolytic transfusion reaction if active at 370c. Aim: To assess the prevalence of A2 and A2B subgroups along with anti-A1 in blood donors of Bangladesh. Setting and design: Cross sectional study in a tertiary care hospital, Bangladesh. Subjects and Methods: The study included blood donor samples received at Transfusion Medicine Department. All samples were typed for ABO and RhD grouping using conventional tube technique. Group A and AB were further subtyped using anti-A1 lectin. Detection of anti-A1 antibody for A2 and A2B individuals was done using A1 red cells. Statistical analysis: The data were analyzed and tabulated by using Microsoft Excel and SPSS (version 26). Fisher’s exact test was used for comparing categorical variables. Results: Out of 1,696 healthy blood donors, blood group O was the highest. The overall phenotypic frequency of all blood groups was O>B>A1>A1B>A2B>A2. A antigen (A and AB Blood Group) was present in 610 (36%). Of these, A1 antigen was present in 599 (98.2%) donors and A2 antigen was present in 11 (1.8%) donors. Of 468 donors with blood group A, 466 (99.6%) belonged to A1 and 2 (0.4%) belonged to A2. Out of 142 group AB donors, A1B was found in 133(93.7%) and A 2B in 9 (6.3%). No anti-A1 was detected in A2 and A2B subgroups. Conclusion: Implementation of A1 and A2 grouping can prevent minor incompatibilities, thus ensuring safe blood transfusion. Pulse Vol.16, 2024 P: 10-14

Maqola ma’lumotlari
MualliflarTamanna Afroz, Abu Jafar Mohammed Saleh
JurnalPULSE
NashriyotPROFI университетининг
ISSN2074-1855, 2235-8668
Nashr sanasi2024-10-21
Jild16
Son1
Betlar10-14
TilIngliz
Ilmiy sohaPsixologiya
DOI10.3329/pulse.v16i1.77064
Indeksga qo‘shilgan2026-09-02

DOI: 10.3329/pulse.v16i1.77064 · Maqolaning asl sahifasi · PDF

Ilmiy soha

Psixologiya

Iqtibos keltirish

APATamanna Afroz, & Abu Jafar Mohammed Saleh (2024). Prevalence of A2 and A2B subgroups and anti-A1 antibody in blood donors at tertiary care center in Bangladesh: A cross sectional study. PULSE, 16(1), 10-14. https://doi.org/10.3329/pulse.v16i1.77064
GOST (OAK)Tamanna Afroz, Abu Jafar Mohammed Saleh Prevalence of A2 and A2B subgroups and anti-A1 antibody in blood donors at tertiary care center in Bangladesh: A cross sectional study // PULSE. – 2024. – T. 16, № 1. – P. 10-14. – DOI: 10.3329/pulse.v16i1.77064.
MLATamanna Afroz, and Abu Jafar Mohammed Saleh. “Prevalence of A2 and A2B subgroups and anti-A1 antibody in blood donors at tertiary care center in Bangladesh: A cross sectional study.” PULSE, 16(1), 10-14, 2024. https://doi.org/10.3329/pulse.v16i1.77064
ChicagoTamanna Afroz, and Abu Jafar Mohammed Saleh. “Prevalence of A2 and A2B subgroups and anti-A1 antibody in blood donors at tertiary care center in Bangladesh: A cross sectional study.” PULSE, 16(1), 10-14 (2024). https://doi.org/10.3329/pulse.v16i1.77064
HarvardTamanna Afroz, and Abu Jafar Mohammed Saleh (2024) ‘Prevalence of A2 and A2B subgroups and anti-A1 antibody in blood donors at tertiary care center in Bangladesh: A cross sectional study’, PULSE, 16(1), 10-14. https://doi.org/10.3329/pulse.v16i1.77064
BibTeX
@article{tamannaafroz2024,
  title = {Prevalence of A2 and A2B subgroups and anti-A1 antibody in blood donors at tertiary care center in Bangladesh: A cross sectional study},
  author = {Tamanna Afroz and Abu Jafar Mohammed Saleh},
  journal = {PULSE},
  year = {2024},
  volume = {16},
  number = {1},
  pages = {10-14},
  doi = {10.3329/pulse.v16i1.77064},
  url = {https://doi.org/10.3329/pulse.v16i1.77064}
}

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