Introduction It is not well-known which indicator, central blood pressure (CBP) or arterial stiffness, has a greater impact on carotid atherosclerosis. This study aimed to assess the associations of carotid atherosclerosis with arterial stiffness and CBP in the same individuals. Methods A total of 142 patients (mean age: 69 years; 43% female) with documented atherosclerotic cardiovascular disease or multiple risk factors were analyzed. Brachial-ankle pulse wave velocity (baPWV) and CBP measurements, along with carotid ultrasound, were performed on the same day. CBP was assessed using radial artery tonometry. Results In simple linear regression analysis, only baPWV exhibited a significant correlation with carotid intima-media thickness (CIMT) (r = 0.272; P = 0.001), whereas none of the CBP parameters (systolic, diastolic, pulse pressures, and augmentation index) correlated with CIMT (P > 0.05 for each). Multiple linear regression analysis indicated that baPWV had no significant association with CIMT after adjusting for age (P = 0.264). A higher baPWV (≥ 1,656 cm/s) was significantly associated with carotid plaque presence, even after accounting for potential confounders (odds ratio: 3.66; 95% confidence interval: 1.65-8.12; P = 0.001). Moreover, as the number of carotid plaques increased, there was a linear rise in baPWV (P < 0.001). None of CBP parameters were associated with the presence of carotid plaque (P > 0.05 for each). Conclusions Among a high-risk Korean population, baPWV demonstrated a stronger association with carotid plaque presence and extent compared to CBP parameters. Thus, baPWV may serve as a valuable marker for identifying carotid plaque.
| Mualliflar | Hack‐Lyoung Kim, Soonil Kwon, Hyun Sung Joh, Woo‐Hyun Lim, Jae‐Bin Seo, Sang‐Hyun Kim, Joo‐Hee Zo, Myung‐A Kim |
|---|---|
| Jurnal | PULSE |
| Nashr sanasi | 2024-12-05 |
| Jild | 13 |
| Son | 1 |
| Betlar | 1-21 |
| Til | en |
| DOI | 10.1159/000543001 |
DOI: 10.1159/000543001 · Maqolaning asl sahifasi
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