Background and Aims: Smoking is a classical and major risk factor for cardiovascular disease. Inflammatory activators and metabolic disorders are the mediators of smoking-induced atherosclerotic progression. The aim of the present study was to investigate whether smoking alter inflammatory or metabolic status and affect subclinical atherosclerosis in apparently healthy persons.Methods: A total number of 149 adults, age 30-60 yrs, were recruited in the study. Participants were divided into sub-groups of smokers (76) and non-smokers (73). All participants were interviewed and underwent physical examinations and blood collection. High-sensitivity C reactive protein (Hs-CRP) was measured to assess degree of underlying inflammation. Fasting plasma glucose and lipid profile were measured to assess metabolic condition. Data were analyzed using statistical Package for Social Program (SPSS) for Windows version 17.Results: Hs-CRP (p=0.017), Fasting glucose (p=0.003), Triglyceride (p=0.005) was significantly high in smokers in comparison with nonsmokers. BMI (p=0.012) and BFM (%) (p= <0.001) showed significantly lower in comparison with the counterpart. HDL-c (p=.030) was also significantly lower in smoker group than non-smoker group. In Spearmans correlation analyses Triglyceride (p=0.037) and smoking (p= 0.042) showed positive correlation with Hs-CRP. HDL-c is less in smoker subjects but not statistically up to the significant level.Conclusion: The rising Hs-CRP concentration reflects presence of chronic subclinical inflammation in middle aged Bangladeshi smokers and thus may have a risk for future cardiovascular disease.Pulse Vol.8 January-December 2015 p.30-37
| Mualliflar | Behterin Rehnuma, Sohely Najneen Eva, Mohammad Ibrahim, Tareak Al Nasir, Liaquat Ali |
|---|---|
| Jurnal | PULSE |
| Nashr sanasi | 2016-06-06 |
| Jild | 8 |
| Son | 1 |
| Betlar | 30-37 |
| Til | en |
| DOI | 10.3329/pulse.v8i1.28099 |
DOI: 10.3329/pulse.v8i1.28099 · Maqolaning asl sahifasi · PDF
The cerebral palsies are a group of conditions due to non progressive damage to the brain before, during or after birth. There are many causes. Although the brain damage itself doesnt change nor is it curable, the…
Gliosarcoma is a rare primary malignancy of the central nervous system, classified by the World Health Organization as a high-grade glioma and a variant of glioblastoma multiforme. A 57-year-old gentleman presented with…
Background: Kiss1, a noble G protein coupled receptor designated as GPR54, was first identified in rat brain in 1999 and orthologue gene identified in human in 2001 the original niche for the function of kisspeptin was…
The clinical use of Renal Doppler ultrasonography is spreading widely because it can assess renal blood flow in a non-invasive evaluation. It is recommended as a screening examination for patients with suspected…
The article by Zachariah and Kovacikova [1] on blood pressure in children sets out the prevailing views on children, which concentrate on the associations of brachial cuff systolic pressure (SP) and diastolic pressure…
Isolated cerebral mucormycosis without rhino-orbital focus is an extremely rare but life-threatening infection of central nervous system that most commonly found in intravenous drug abuser. We present a case of isolated…
Abstract not availablePulse Vol.8 January-December 2015 p.7
Myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction. The disease is characterized by exacerbation and remission of the symptoms from time to time. Myasthenic crisis is a serious complication…
A 56 years old diabetic hypertensive male was admitted through neurosurgery OPD with the complaint of vision problems in the right eye for the last 1 and 1/2 years. Peri-metry reveals bilateral temporal field defects…
UNLABELLED: Invasive and noninvasive methods for evaluating the effects of hemodynamics on progression of left ventricular hypertrophy (LVH) in patients with chronic kidney disease (CKD) have been proposed. Central…