Kinetic investigation of the SN2 reaction between piperidine and chloroacetic acid using atr-ftir spectroscopy

Sadoqat Mamatkulova, Oytura S. MAKSUMOVA

Kimyo va kimyo texnologiyasi · 2026-yil

Annotatsiya

In this study, the kinetic characteristics of the nucleophilic substitution (SN2) reaction between piperidine and chloroacetic acid were investigated in real time at 50, 60, and 70 °C using ATR-FTIR spectroscopy. The spectral analysis revealed a gradual decrease in the C–Cl stretching vibration in the 710–730 cm⁻¹ region and a simultaneous increase in absorption bands corresponding to the C–N bond in the 1020–1250 cm⁻¹ region, confirming the consistent progression of the reaction. Analysis of the conversion function X(t) showed values of X = 0.669 at 50 °C, X = 0.826 at 60 °C, and X = 0.970 at 70 °C, indicating a substantial acceleration of the reaction rate with increasing temperature. The dX/dt–t profiles displayed a maximum initial reaction rate followed by exponential decay. Linear regression analysis demonstrated excellent agreement with the first-order kinetic model at all temperatures (R² = 0.97–0.999), and the rate constants increased from 0.0078 → 0.0106 → 0.0143 min⁻¹. Arrhenius analysis yielded an activation energy of 27.9 kJ·mol⁻¹. These results confirm that the piperidine–chloroacetate system proceeds via an SN2 mechanism and demonstrate that ATR-FTIR spectroscopy provides high sensitivity and accuracy for real-time monitoring of reaction processes.

Maqola ma’lumotlari
MualliflarSadoqat Mamatkulova, Oytura S. MAKSUMOVA
JurnalKimyo va kimyo texnologiyasi
NashriyotТошкент кимё-технология институти
ISSN1992-9498, 2181-1121
Nashr sanasi2026-03-27
Jild2026
Son1
TilIngliz
Ilmiy sohaKimyo
DOI10.70189/1992-9498.1713
Indeksga qo‘shilgan2026-09-02

DOI: 10.70189/1992-9498.1713 · Maqolaning asl sahifasi · PDF

Ilmiy soha

Kimyo

Iqtibos keltirish

APASadoqat Mamatkulova, & Oytura S. MAKSUMOVA (2026). KINETIC INVESTIGATION OF THE SN2 REACTION BETWEEN PIPERIDINE AND CHLOROACETIC ACID USING ATR-FTIR SPECTROSCOPY. Kimyo va kimyo texnologiyasi, 2026(1). https://doi.org/10.70189/1992-9498.1713
GOST (OAK)Sadoqat Mamatkulova, Oytura S. MAKSUMOVA KINETIC INVESTIGATION OF THE SN2 REACTION BETWEEN PIPERIDINE AND CHLOROACETIC ACID USING ATR-FTIR SPECTROSCOPY // Kimyo va kimyo texnologiyasi. – 2026. – T. 2026, № 1. – DOI: 10.70189/1992-9498.1713.
MLASadoqat Mamatkulova, and Oytura S. MAKSUMOVA. “KINETIC INVESTIGATION OF THE SN2 REACTION BETWEEN PIPERIDINE AND CHLOROACETIC ACID USING ATR-FTIR SPECTROSCOPY.” Kimyo va kimyo texnologiyasi, 2026(1), 2026. https://doi.org/10.70189/1992-9498.1713
ChicagoSadoqat Mamatkulova, and Oytura S. MAKSUMOVA. “KINETIC INVESTIGATION OF THE SN2 REACTION BETWEEN PIPERIDINE AND CHLOROACETIC ACID USING ATR-FTIR SPECTROSCOPY.” Kimyo va kimyo texnologiyasi, 2026(1) (2026). https://doi.org/10.70189/1992-9498.1713
HarvardSadoqat Mamatkulova, and Oytura S. MAKSUMOVA (2026) ‘KINETIC INVESTIGATION OF THE SN2 REACTION BETWEEN PIPERIDINE AND CHLOROACETIC ACID USING ATR-FTIR SPECTROSCOPY’, Kimyo va kimyo texnologiyasi, 2026(1). https://doi.org/10.70189/1992-9498.1713
BibTeX
@article{sadoqatmamatkulova2026,
  title = {KINETIC INVESTIGATION OF THE SN2 REACTION BETWEEN PIPERIDINE AND CHLOROACETIC ACID USING ATR-FTIR SPECTROSCOPY},
  author = {Sadoqat Mamatkulova and Oytura S. MAKSUMOVA},
  journal = {Kimyo va kimyo texnologiyasi},
  year = {2026},
  volume = {2026},
  number = {1},
  doi = {10.70189/1992-9498.1713},
  url = {https://doi.org/10.70189/1992-9498.1713}
}

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