This article studies feasibilities of making an implant-film for treatment of burn wound, based on silver nanoparticles (AgNPs) stabilized by sodiumcarboxymethylcellulose (Na-CMC) with degrees of substitution (DS) 0.65-0.90 and polymerization (DP) 200-600 synthesized using a photochemical method. The structural, physical and chemical, and physicalmechanical, burn wound healing properties as well as antimicrobial effects of implant-films containing the Na-CMC and AgNPs have been investigated. The shape, quantity, and size of the AgNPs embedded into the Na-CMC films were determined by UV-Vis spectroscopy, dynamic light scattering (DLS), atomic force microscopy (AFM) and transmission electron microscopy (TEM). It was found that the increase of silver nitrate concentration in solution of Na-CMC followed by photoirradiation leads to changes of AgNPs size and shape. It was found out that Na-CMC films containing AgNPs in the size ranging from 5 to 35 nm had enhanced the microbicide effects and burn wound healing properties within 14 days.
| Mualliflar | A. A. Sarymsakov, Khaydar E. Yunusov, J. Z. Jalilov, D. Sh. Saburova, А. Dj. Fayazov, U. R. Kamilov |
|---|---|
| Jurnal | Илм-фан ва инновацион ривожланиш |
| Nashr sanasi | 2023-02-24 |
| Jild | 5 |
| Son | 1 |
| Betlar | 56-68 |
| Til | en |
| DOI | 10.36522/2181-9637-2022-1-6 |
DOI: 10.36522/2181-9637-2022-1-6 · Maqolaning asl sahifasi
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