SYNTHESIS OF 6-SUBSTITUTED QUINAZOLINE-4-THIONES BY THE SUZUKI MIYAURA METHOD

D. Turgunov, Azizbek Nasrullaev, Khurshed Bozorov, N. Lifei, Haji Akber Aisa

Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi · 2025-yil

Annotatsiya

Initially, using the cyclization methods known to us, quinazolin-4-one derivatives containing bromine in the 6 position were synthesized and converted into 6-bromo-quinazolin 4-thiones using Lawesson's reagent. The thione derivatives were reacted with aromatic boronic acids in the presence of appropriate bases, palladium catalysts, and solvents, their chemical properties were studied and optimal conditions were selected. The structures of the resulting new compounds were analyzed based on 1H NMR, 13C NMR, MS, and MP analyses.

Maqola ma’lumotlari
MualliflarD. Turgunov, Azizbek Nasrullaev, Khurshed Bozorov, N. Lifei, Haji Akber Aisa
JurnalSamarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi
Nashr sanasi2025-03-29
Jild1
Son1
Betlar18-22
Tilen
DOI10.59251/2181-1296.2025.v1.149.2.3209

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