Comparative study of clinical complications in elderly patients with chronic heart failure and atrial fibrillation with and without COVID-19 infection

Avazbekov B.A., Tulaboyeva G.M., Tursunov Kh.Kh.

Вестник Ассоциации пульмонологов Центральной Азии · 2026-yil

Annotatsiya

This study aimed to evaluate and compare the clinical course and complications of chronic heart failure (CHF) and atrial fibrillation (AF) in elderly patients with and without a history of COVID-19 infection. A retrospective cohort study was conducted including 285 patients aged ≥60 years diagnosed with CHF and AF between 2021 and 2023. Patients were divided into two groups: Group 1 (n=145) – CHF + AF with previous COVID-19 infection; Group 2 (n=140) – CHF + AF without COVID-19. Clinical status was assessed using NYHA and EHRA classifications. Echocardiographic parameters, laboratory findings, rehospitalization rate, thromboembolic complications, and mortality were analyzed. Patients with prior COVID-19 demonstrated significantly higher rates of NYHA class IV (61.1% vs. 38.6%, p<0.05), reduced left ventricular ejection fraction (35±5% vs. 45±6%, p<0.01), increased D-dimer levels, and greater incidence of thromboembolic events (12.4% vs. 5.7%, p<0.05). Rehospitalization and decompensation episodes were also more frequent in the post-COVID group.The findings suggest that COVID-19 infection is associated with worsened cardiac remodeling, increased inflammatory and prothrombotic activity, and more severe clinical progression of CHF and AF in elderly patients. Post-COVID status should therefore be considered an independent aggravating factor in risk stratification and management strategies.

Maqola ma’lumotlari
MualliflarAvazbekov B.A., Tulaboyeva G.M., Tursunov Kh.Kh.
JurnalВестник Ассоциации пульмонологов Центральной Азии
NashriyotАссоциация Пульмонологов Центральной Азии
ISSN2181-4988
Nashr sanasi2026-04-13
Jild18
Son13
Betlar182-187
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

Chronic heart failure, atrial fibrillation, COVID-19, elderly patients, cardiac remodeling, thromboembolism, rehospitalization, inflammation.

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAAvazbekov B.A., Tulaboyeva G.M., Tursunov Kh.Kh. (2026). COMPARATIVE STUDY OF CLINICAL COMPLICATIONS IN ELDERLY PATIENTS WITH CHRONIC HEART FAILURE AND ATRIAL FIBRILLATION WITH AND WITHOUT COVID-19 INFECTION. Вестник Ассоциации пульмонологов Центральной Азии, 18(13), 182-187. https://journals.tnmu.uz/index.php/bapca/article/view/4500
GOST (OAK)Avazbekov B.A., Tulaboyeva G.M., Tursunov Kh.Kh. COMPARATIVE STUDY OF CLINICAL COMPLICATIONS IN ELDERLY PATIENTS WITH CHRONIC HEART FAILURE AND ATRIAL FIBRILLATION WITH AND WITHOUT COVID-19 INFECTION // Вестник Ассоциации пульмонологов Центральной Азии. – 2026. – T. 18, № 13. – P. 182-187.
MLAAvazbekov B.A., Tulaboyeva G.M., Tursunov Kh.Kh. “COMPARATIVE STUDY OF CLINICAL COMPLICATIONS IN ELDERLY PATIENTS WITH CHRONIC HEART FAILURE AND ATRIAL FIBRILLATION WITH AND WITHOUT COVID-19 INFECTION.” Вестник Ассоциации пульмонологов Центральной Азии, 18(13), 182-187, 2026. https://journals.tnmu.uz/index.php/bapca/article/view/4500
ChicagoAvazbekov B.A., Tulaboyeva G.M., Tursunov Kh.Kh. “COMPARATIVE STUDY OF CLINICAL COMPLICATIONS IN ELDERLY PATIENTS WITH CHRONIC HEART FAILURE AND ATRIAL FIBRILLATION WITH AND WITHOUT COVID-19 INFECTION.” Вестник Ассоциации пульмонологов Центральной Азии, 18(13), 182-187 (2026). https://journals.tnmu.uz/index.php/bapca/article/view/4500
HarvardAvazbekov B.A., Tulaboyeva G.M., Tursunov Kh.Kh (2026) ‘COMPARATIVE STUDY OF CLINICAL COMPLICATIONS IN ELDERLY PATIENTS WITH CHRONIC HEART FAILURE AND ATRIAL FIBRILLATION WITH AND WITHOUT COVID-19 INFECTION’, Вестник Ассоциации пульмонологов Центральной Азии, 18(13), 182-187. https://journals.tnmu.uz/index.php/bapca/article/view/4500
BibTeX
@article{avazbekovbatulaboyevagmtursunovkhkh2026,
  title = {COMPARATIVE STUDY OF CLINICAL COMPLICATIONS IN ELDERLY PATIENTS WITH CHRONIC HEART FAILURE AND ATRIAL FIBRILLATION WITH AND WITHOUT COVID-19 INFECTION},
  author = {Avazbekov B.A., Tulaboyeva G.M., Tursunov Kh.Kh.},
  journal = {Вестник Ассоциации пульмонологов Центральной Азии},
  year = {2026},
  volume = {18},
  number = {13},
  pages = {182-187},
  url = {https://journals.tnmu.uz/index.php/bapca/article/view/4500}
}

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