This study aimed to evaluate and compare the clinical course and complications of chronic heart failure (CHF) and atrial fibrillation (AF) in elderly patients with and without a history of COVID-19 infection. A retrospective cohort study was conducted including 285 patients aged ≥60 years diagnosed with CHF and AF between 2021 and 2023. Patients were divided into two groups: Group 1 (n=145) – CHF + AF with previous COVID-19 infection; Group 2 (n=140) – CHF + AF without COVID-19. Clinical status was assessed using NYHA and EHRA classifications. Echocardiographic parameters, laboratory findings, rehospitalization rate, thromboembolic complications, and mortality were analyzed. Patients with prior COVID-19 demonstrated significantly higher rates of NYHA class IV (61.1% vs. 38.6%, p<0.05), reduced left ventricular ejection fraction (35±5% vs. 45±6%, p<0.01), increased D-dimer levels, and greater incidence of thromboembolic events (12.4% vs. 5.7%, p<0.05). Rehospitalization and decompensation episodes were also more frequent in the post-COVID group.The findings suggest that COVID-19 infection is associated with worsened cardiac remodeling, increased inflammatory and prothrombotic activity, and more severe clinical progression of CHF and AF in elderly patients. Post-COVID status should therefore be considered an independent aggravating factor in risk stratification and management strategies.
| Mualliflar | Avazbekov B.A., Tulaboyeva G.M., Tursunov Kh.Kh. |
|---|---|
| Jurnal | Вестник Ассоциации пульмонологов Центральной Азии |
| Nashr sanasi | 2026-04-13 |
| Jild | 18 |
| Son | 13 |
| Betlar | 182-187 |
| Til | Rus |
Chronic heart failure, atrial fibrillation, COVID-19, elderly patients, cardiac remodeling, thromboembolism, rehospitalization, inflammation.
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Вестник Ассоциации пульмонологов Центральной Азии — barcha maqolalar