CLINICAL EVIDENCE OF KETOGENIC DIETARY INTERVENTIONS IN PARKINSON’S DISEASE: IMPACT ON BIOMARKERS, DEPRESSION, ANXIETY, AND QUALITY OF LIFE

Khodjiyeva D.T., Bafoyeva Z.B.

Вестник Ассоциации пульмонологов Центральной Азии · 2026-yil

Annotatsiya

Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor symptoms. Ketogenic diets (KDs), high in fat and low in carbohydrates, have gained attention as potential adjunctive interventions for PD due to their neuroprotective, anti-inflammatory, and mitochondrial-enhancing effects. This review summarizes clinical evidence on the effects of ketogenic dietary interventions in PD, with a focus on biomarkers, depression, anxiety, and quality of life (QoL). Emerging data suggest that KD may improve motor and non-motor symptoms, modulate metabolic and inflammatory biomarkers, and enhance overall well-being. However, evidence is limited by small sample sizes, short intervention durations, and heterogeneity in dietary protocols. Further large-scale, randomized controlled trials are required.

Maqola ma’lumotlari
MualliflarKhodjiyeva D.T., Bafoyeva Z.B.
JurnalВестник Ассоциации пульмонологов Центральной Азии
Nashr sanasi2026-04-13
Jild18
Son13
Betlar172-174
TilRus

Kalit so‘zlar

Parkinson’s disease; ketogenic diet; ketosis; biomarkers; depression; anxiety; quality of life; neuroprotection; clinical trials

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