Rheumatoid arthritis: new treatment approaches - a comparative evidence review

Anorboyev M.Kh., Khojanazarov I.E., Akhmedov Kh.S., Mullokulov J.J.

Вестник Ассоциации пульмонологов Центральной Азии · 2025-yil

Annotatsiya

Rheumatoid arthritis (RA) is a systemic autoimmune disease that has undergone a therapeutic revolution over the past two decades. Conventional synthetic DMARDs remain foundational, but the introduction of biologic and targeted synthetic DMARDs has transformed outcomes. This article reviews pivotal randomized controlled trials, comparative efficacy and safety data, and evolving treatment algorithms. Quantitative comparisons including absolute risk reduction (ARR), relative risk (RR), and number needed to treat (NNT) are provided for head-to-head studies, alongside safety analyses from ORAL Surveillance and regulatory guidance. A treat-to-target approach, precision medicine, and risk stratification remain essential for optimizing outcomes in 2025 and beyond.

Maqola ma’lumotlari
MualliflarAnorboyev M.Kh., Khojanazarov I.E., Akhmedov Kh.S., Mullokulov J.J.
JurnalВестник Ассоциации пульмонологов Центральной Азии
NashriyotАссоциация Пульмонологов Центральной Азии
ISSN2181-4988
Nashr sanasi2025-10-18
Jild13
Son8
Betlar62-66
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

Upadacitinib, bDMARDs, tofacitinib, baricitinib

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAAnorboyev M.Kh., Khojanazarov I.E., Akhmedov Kh.S., Mullokulov J.J. (2025). RHEUMATOID ARTHRITIS: NEW TREATMENT APPROACHES - A COMPARATIVE EVIDENCE REVIEW. Вестник Ассоциации пульмонологов Центральной Азии, 13(8), 62-66. https://journals.tnmu.uz/index.php/bapca/article/view/2476
GOST (OAK)Anorboyev M.Kh., Khojanazarov I.E., Akhmedov Kh.S., Mullokulov J.J. RHEUMATOID ARTHRITIS: NEW TREATMENT APPROACHES - A COMPARATIVE EVIDENCE REVIEW // Вестник Ассоциации пульмонологов Центральной Азии. – 2025. – T. 13, № 8. – P. 62-66.
MLAAnorboyev M.Kh., Khojanazarov I.E., Akhmedov Kh.S., Mullokulov J.J. “RHEUMATOID ARTHRITIS: NEW TREATMENT APPROACHES - A COMPARATIVE EVIDENCE REVIEW.” Вестник Ассоциации пульмонологов Центральной Азии, 13(8), 62-66, 2025. https://journals.tnmu.uz/index.php/bapca/article/view/2476
ChicagoAnorboyev M.Kh., Khojanazarov I.E., Akhmedov Kh.S., Mullokulov J.J. “RHEUMATOID ARTHRITIS: NEW TREATMENT APPROACHES - A COMPARATIVE EVIDENCE REVIEW.” Вестник Ассоциации пульмонологов Центральной Азии, 13(8), 62-66 (2025). https://journals.tnmu.uz/index.php/bapca/article/view/2476
HarvardAnorboyev M.Kh., Khojanazarov I.E., Akhmedov Kh.S., Mullokulov J.J (2025) ‘RHEUMATOID ARTHRITIS: NEW TREATMENT APPROACHES - A COMPARATIVE EVIDENCE REVIEW’, Вестник Ассоциации пульмонологов Центральной Азии, 13(8), 62-66. https://journals.tnmu.uz/index.php/bapca/article/view/2476
BibTeX
@article{anorboyevmkhkhojanazarovieakhmedovkhsmullokulovjj2025,
  title = {RHEUMATOID ARTHRITIS: NEW TREATMENT APPROACHES - A COMPARATIVE EVIDENCE REVIEW},
  author = {Anorboyev M.Kh., Khojanazarov I.E., Akhmedov Kh.S., Mullokulov J.J.},
  journal = {Вестник Ассоциации пульмонологов Центральной Азии},
  year = {2025},
  volume = {13},
  number = {8},
  pages = {62-66},
  url = {https://journals.tnmu.uz/index.php/bapca/article/view/2476}
}

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