The study aimed to evaluate volumetric outcomes, angiogenic biomarkers and microcirculation parameters following laser patterned microcoagulation (LPM) sessions on CTG-grafted sites. 25 patients with soft tissue dehiscence underwent STG using CTG. Two weeks after STG, LPM sessions were performed on one side of the jaw, while the contralateral side healed without laser application (split-mouth study). LPM was conducted using a 1550 nm diode laser. The analysis of outcomes was based on the KMW and MT gains, microcirculation parameters, and angiogenic biomarkers release in gingival crevicular fluid (GCF) of two adjacent natural teeth. Measurements showed that KMW and MT gain were significantly higher at LPM sites. LPM improved microcirculation and venous outflow, decreased peripheral flow resistance, and normalized vascular tonus. Vascular endothelial growth factor and platelet-derived growth factor-BB values were significantly higher in GCF from the LPM sites. LPM has a positive effect on outcomes of soft tissue augmentation by promoting neocollagenesis, cell proliferation and enhancing graft revascularization.
| Mualliflar | Shomurodov K.E., Mirkhusanova R.S. |
|---|---|
| Jurnal | Ёш олимлар тиббиёт журнали |
| Nashr sanasi | 2026-06-20 |
| Son | 18 |
| Betlar | 93-99 |
| Til | Rus |
diode laser, soft tissue augmentation, microcirculation, biomarker, dental implantation.
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