The purpose of the study: to approximate the dynamics of clinical and hemodynamic indicators in the acute period of ischemic stroke disease, as well as to improve the standard treatment measure. Research material and techniques. As a research material, 50 patients with ischemic stroke disease were monitored in the intensive neurology and neurology departments of the TTA multidisciplinary clinic, confirmed by multispiral computed tomography examination. The patients under study (n=50) were conditionally divided into 2 groups, that is, 25 patients who received basis therapy as well as standard therapy in the treatment of ischemic stroke, and 25 patients who took 10 ml of Lidosinate intravenously in 100 ml of saline solution for 10 days against basis therapy, standard therapy and brain edema. Results: All (n=50) patients were tested on the 1st, 2nd days of hospitalization and on the 10th day of treatment, clinical neurologic (NIHSS and Scandinavian scale), angiological (duplex scanning of cervical trunk blood vessels), and neurovisualization, i.e. cranial MSKT, on the 1st day of the diseaseAmong the objective signs, among patients in one group of patients, the increase in pay reflexes, central paralysis of nerve VII and XII and cognitive disorders were significantly more pronounced than in the rest of the symptoms NIHSS Scale decreased by 32.35%, and on the Scandinavian scale – increased by 12.79% compared to patients who were not treated with Lidosinate (р<0,05). Conclusion: Thus, the results of the study showed that the use of Lidosinate reduces the effects of ischemia and hypoxia by normalizing the permeability of brain tissue, which plays an important role in early and late neuronal injury processes in acute ischemic stroke. Neurological scales have shown that the use of Lidosinate is a significant improvement in the clinical picture of the disease, which is confirmed by a decrease in the severity of neurological deficits according to clinical indications. The use of lidosinate improves effective intrasserebral blood flow as a result of improved venous circulation, which in turn leads to improved arterial perfusion of the brain.
| Mualliflar | Асадуллаев Мақсуд Махмудович, Соҳибназаров Нодиржон Ғанижонович, Атаниязов Махсуджан Камалиддинович, Вахабова Наргиза Мақсудовна, Шамсиева Умида Абдувахидовна |
|---|---|
| Jurnal | Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research |
| Nashr sanasi | 2024-05-27 |
| Jild | 5 |
| Son | 2 |
| Til | O‘zbek |
Tashkent Medical Academy, ischemic stroke, NIHSS and Scandinavian scales, duplex scanning, MSKT, Тошкент тиббиёт академияси, ишемик инсульт, NIHSS ва Скандинав шкалалар, дуплекс сканерлаш, МСКТ
A modern approach to the complex diagnosis of both transcranial and nasal liquorrhea is considered. The terminology and the most common and used variants of classification of liquorrhea are given. The epidemiology and…
This article analyzed literary information about the features of the development of neurological disorders in cystic fibrosis (CF), about modern views on the early diagnosis of this pathology. A generalized analysis of…
Back pain in pregnancy: causes of occurrence, in what diseases it occurs, diagnosis and treatment methods. Back pain is one of the most frequent complaints of pregnant women at appointments at antenatal clinics…
Childhood Cerebral Palsy (CP) occurs due to brain damage during the perinatal period. CP is characterized by impaired motor functions, increased muscle tone, and other symptoms. Selective dorsal rhizotomy is the most…
The article deals with the main factors of students' stress, the dynamics of its course. The results of students' examination of exam stress; practical methods of correction used by students to relieve mental tension…
Juvenile myoclonic epilepsy (JME) is a common idiopathic epilepsy, accounting for 10% of all epilepsies. It is characterized as a syndrome of generalized genetic epilepsy with a peak development at the age of 12-18…
Hemorrhagic stroke whitekir survived 75 patients. Psychological, clinical, instrumental and neuropsychological treatment is the main group of 42 patients of early rehabilitation, verticalization and hemorrhagic stroke…
Cerebrovascular diseases (CVD) have remained an urgent medical and social problem of modern society over the past decades. One of the main pathogenetic subtype of ischemic stroke is…
The purpose of this work was to develop and implement a diagnostic and treatment algorithm, and systematize indications for differentiated treatment of patients with traumatic intracranial hematomas. Developed and…
despite the existence of several projects in the world for the study of neoplasms of the central nervous system, the data of primary spinal cord tumors(PSCT) have been little studied, there are no single…