THE SIGNIFICANCE OF CORONARY CALCIUM IN THE DIAGNOSIS AND CLINICAL COURSE OF CHRONIC ISCHEMIC HEART DISEASE

Shukurdjanova, Surayyo Makhmudovna, Rajabova, Rano Shavkatovna, Narzullayev, Shakhruz Yorkinugli

Ёш олимлар тиббиёт журнали · 2025-yil

Annotatsiya

Calcium is found in teeth and bone, approximately 1% is dissolved in the bloodstream. As the human body ages, calcium is deposited in various body parts. Arterial calcification is closely related to vascular injury, inflammation, and repair. Calcification occurs very early in atherosclerosis; it is only detectable through imaging modalities when it accumulates in tissue and vasculature. This accumulation typically occurs after age 40, and most individuals older than 60 have diffuse calcification. Coronary vessel calcification is deeply linked with atherosclerosis expansion, which is the ancestor of cardiovascular diseases (CVD) amplification. A close relationship exists between coronary calcium burden and atherosclerosis despite not all plaques being calcified. The presence and extent of coronary artery calcification (CAC) provides direct evidence of coronary artery disease. Unstable angina is characterized by lesions with smaller calcium deposits described as spotty or speckled; fewer, larger calcium deposits often characterize stable angina. Lesions without calcium are usually nonocclusive (<25% stenosis). CAC independently predicts future major adverse cardiovascular events (MACE) more than other noninvasive modalities.

Maqola ma’lumotlari
MualliflarShukurdjanova, Surayyo Makhmudovna, Rajabova, Rano Shavkatovna, Narzullayev, Shakhruz Yorkinugli
JurnalЁш олимлар тиббиёт журнали
Nashr sanasi2025-06-05
Son14
Betlar256-261
TilRus

Kalit so‘zlar

atherosclerosis, myocardial infarction, calcium scoring, coronary artery disease, computed tomography, cardiovascular events.

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