Biological activity of 3-AMINO-4-METHYL benzoic acid and its supramolecular compound with nickel triethanolamine complex

Farrukhbek, Oybek ugli Mamatsabirov, Abbos, Bozor ugli Mambetov, Azizbek, Jovliyev Muxtor o'g'li, Azizbek, Serobov Nizomjonovich, Bakhtiyar, Tulaganovich Ibragimov

Қўқон ДПИ. Илмий хабарлар · 2026-yil

Annotatsiya

A supramolecular nickel(II) complex, bis[triethanolamine- κN,O,O′]nickel(II) bis(3-amino-4-methylbenzoate), [Ni(TEA)2](AMB)2, was synthesized and comprehensively characterized by and single-crystal X-ray diffraction. Antimicrobial assays show that the complex exhibits moderate, broad-spectrum antibacterial activity and performs better than its individual components, though it remains less active than ciprofloxacin. Molecular docking studies predict the strongest binding to Bacillus subtilis, supported by a favourable cavity size and π-π interactions with a porphyrin cofactor.

Maqola ma’lumotlari
MualliflarFarrukhbek, Oybek ugli Mamatsabirov, Abbos, Bozor ugli Mambetov, Azizbek, Jovliyev Muxtor o'g'li, Azizbek, Serobov Nizomjonovich, Bakhtiyar, Tulaganovich Ibragimov
JurnalҚўқон ДПИ. Илмий хабарлар
NashriyotҚўқон давлат педагогика институти
ISSN3030-3958
Nashr sanasi2026-09-05
Jild8
Son6
Betlar78-86
TilIngliz
DOI10.70728/a.series.tab.v08.i06.012
Indeksga qo‘shilgan2026-09-06

DOI: 10.70728/a.series.tab.v08.i06.012 · Maqolaning asl sahifasi

Kalit so‘zlar

nickel(II)complex, 3-amino-4-methylbenzoate, triethanolamine, synthesis, SCXRD, coordination geometry, antimicrobial activity, molecular docking.

Iqtibos keltirish

APAFarrukhbek, Oybek ugli Mamatsabirov, Abbos, Bozor ugli Mambetov, Azizbek, Jovliyev Muxtor o'g'li, Azizbek, Serobov Nizomjonovich, & Bakhtiyar, Tulaganovich Ibragimov (2026). BIOLOGICAL ACTIVITY OF 3-AMINO-4-METHYL BENZOIC ACID AND ITS SUPRAMOLECULAR COMPOUND WITH NICKEL TRIETHANOLAMINE COMPLEX. Қўқон ДПИ. Илмий хабарлар, 8(6), 78-86. https://doi.org/10.70728/a.series.tab.v08.i06.012
GOST (OAK)Farrukhbek, Oybek ugli Mamatsabirov va b. BIOLOGICAL ACTIVITY OF 3-AMINO-4-METHYL BENZOIC ACID AND ITS SUPRAMOLECULAR COMPOUND WITH NICKEL TRIETHANOLAMINE COMPLEX // Қўқон ДПИ. Илмий хабарлар. – 2026. – T. 8, № 6. – P. 78-86. – DOI: 10.70728/a.series.tab.v08.i06.012.
MLAFarrukhbek, Oybek ugli Mamatsabirov, Abbos, Bozor ugli Mambetov, Azizbek, Jovliyev Muxtor o'g'li, Azizbek, Serobov Nizomjonovich, and Bakhtiyar, Tulaganovich Ibragimov. “BIOLOGICAL ACTIVITY OF 3-AMINO-4-METHYL BENZOIC ACID AND ITS SUPRAMOLECULAR COMPOUND WITH NICKEL TRIETHANOLAMINE COMPLEX.” Қўқон ДПИ. Илмий хабарлар, 8(6), 78-86, 2026. https://doi.org/10.70728/a.series.tab.v08.i06.012
ChicagoFarrukhbek, Oybek ugli Mamatsabirov, Abbos, Bozor ugli Mambetov, Azizbek, Jovliyev Muxtor o'g'li, Azizbek, Serobov Nizomjonovich, and Bakhtiyar, Tulaganovich Ibragimov. “BIOLOGICAL ACTIVITY OF 3-AMINO-4-METHYL BENZOIC ACID AND ITS SUPRAMOLECULAR COMPOUND WITH NICKEL TRIETHANOLAMINE COMPLEX.” Қўқон ДПИ. Илмий хабарлар, 8(6), 78-86 (2026). https://doi.org/10.70728/a.series.tab.v08.i06.012
HarvardFarrukhbek, Oybek ugli Mamatsabirov, Abbos, Bozor ugli Mambetov, Azizbek, Jovliyev Muxtor o'g'li, Azizbek, Serobov Nizomjonovich, and Bakhtiyar, Tulaganovich Ibragimov (2026) ‘BIOLOGICAL ACTIVITY OF 3-AMINO-4-METHYL BENZOIC ACID AND ITS SUPRAMOLECULAR COMPOUND WITH NICKEL TRIETHANOLAMINE COMPLEX’, Қўқон ДПИ. Илмий хабарлар, 8(6), 78-86. https://doi.org/10.70728/a.series.tab.v08.i06.012
BibTeX
@article{farrukhbekoybekuglimamatsabirov2026,
  title = {BIOLOGICAL ACTIVITY OF 3-AMINO-4-METHYL BENZOIC ACID AND ITS SUPRAMOLECULAR COMPOUND WITH NICKEL TRIETHANOLAMINE COMPLEX},
  author = {Farrukhbek, Oybek ugli Mamatsabirov and Abbos, Bozor ugli Mambetov and Azizbek, Jovliyev Muxtor o'g'li and Azizbek, Serobov Nizomjonovich and Bakhtiyar, Tulaganovich Ibragimov},
  journal = {Қўқон ДПИ. Илмий хабарлар},
  year = {2026},
  volume = {8},
  number = {6},
  pages = {78-86},
  doi = {10.70728/a.series.tab.v08.i06.012},
  url = {https://doi.org/10.70728/a.series.tab.v08.i06.012}
}

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