A systematic review examining the application of STEM cell–based therapy as an innovative therapeutic intervention for parkinson's disease stm: parkinson kasalligini davolashning innovatsion u

Rakhimbaeva, Gulnora Sattarovna, Musaeva , Yulduz Alpisovna, Akramova , Dilshoda Turdikulovna, Kasimova , Oksana Olegovna

Гуманитар ва табиий фанлар журнали · 2024-yil

Annotatsiya

In recent decades, treatment methods aimed at reversing the progression of Parkinson's disease (PD) have generated significant interest. PD is characterized by a gradual loss of dopaminergic (DA) neurons and a decrease in dopamine levels in the striatum. Current challenges include optimizing neuroprotective strategies, developing personalized drug therapies, and minimizing side effects from long–term administration of pharmacological agents used to alleviate short–term motor symptoms. Cell transplantation of DA cells into the brains of PD patients to replace degenerated DA has the potential to change the treatment paradigm. This review provides updated information on the current progress of transplanting DA neurons derived from stem cells as a therapeutic alternative for PD. Sources of cells for transplantation are described, and the focus is on cell evaluation methods such as identification of genetic markers, single–cell sequencing, and visualization techniques used to assess cell survival and function.

Maqola ma’lumotlari
MualliflarRakhimbaeva, Gulnora Sattarovna, Musaeva , Yulduz Alpisovna, Akramova , Dilshoda Turdikulovna, Kasimova , Oksana Olegovna
JurnalГуманитар ва табиий фанлар журнали
NashriyotEMU University
ISSN2026-2027, 2181-4007
Nashr sanasi2024-08-15
Son13
Betlar46-49
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

parkinson's disease (pd), immunosuppression, stem cells, da neurons, transplantation, sequencing.

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APARakhimbaeva, Gulnora Sattarovna, Musaeva , Yulduz Alpisovna, Akramova , Dilshoda Turdikulovna, & Kasimova , Oksana Olegovna (2024). A SYSTEMATIC REVIEW EXAMINING THE APPLICATION OF STEM CELL–BASED THERAPY AS AN INNOVATIVE THERAPEUTIC INTERVENTION FOR PARKINSON'S DISEASE STM: PARKINSON KASALLIGINI DAVOLASHNING INNOVATSION U. Гуманитар ва табиий фанлар журнали, (13), 46-49. https://journals.tnmu.uz/index.php/gtfj/article/view/592
GOST (OAK)Rakhimbaeva, Gulnora Sattarovna va b. A SYSTEMATIC REVIEW EXAMINING THE APPLICATION OF STEM CELL–BASED THERAPY AS AN INNOVATIVE THERAPEUTIC INTERVENTION FOR PARKINSON'S DISEASE STM: PARKINSON KASALLIGINI DAVOLASHNING INNOVATSION U // Гуманитар ва табиий фанлар журнали. – 2024. – № 13. – P. 46-49.
MLARakhimbaeva, Gulnora Sattarovna, Musaeva , Yulduz Alpisovna, Akramova , Dilshoda Turdikulovna, and Kasimova , Oksana Olegovna. “A SYSTEMATIC REVIEW EXAMINING THE APPLICATION OF STEM CELL–BASED THERAPY AS AN INNOVATIVE THERAPEUTIC INTERVENTION FOR PARKINSON'S DISEASE STM: PARKINSON KASALLIGINI DAVOLASHNING INNOVATSION U.” Гуманитар ва табиий фанлар журнали, (13), 46-49, 2024. https://journals.tnmu.uz/index.php/gtfj/article/view/592
ChicagoRakhimbaeva, Gulnora Sattarovna, Musaeva , Yulduz Alpisovna, Akramova , Dilshoda Turdikulovna, and Kasimova , Oksana Olegovna. “A SYSTEMATIC REVIEW EXAMINING THE APPLICATION OF STEM CELL–BASED THERAPY AS AN INNOVATIVE THERAPEUTIC INTERVENTION FOR PARKINSON'S DISEASE STM: PARKINSON KASALLIGINI DAVOLASHNING INNOVATSION U.” Гуманитар ва табиий фанлар журнали, (13), 46-49 (2024). https://journals.tnmu.uz/index.php/gtfj/article/view/592
HarvardRakhimbaeva, Gulnora Sattarovna, Musaeva , Yulduz Alpisovna, Akramova , Dilshoda Turdikulovna, and Kasimova , Oksana Olegovna (2024) ‘A SYSTEMATIC REVIEW EXAMINING THE APPLICATION OF STEM CELL–BASED THERAPY AS AN INNOVATIVE THERAPEUTIC INTERVENTION FOR PARKINSON'S DISEASE STM: PARKINSON KASALLIGINI DAVOLASHNING INNOVATSION U’, Гуманитар ва табиий фанлар журнали, (13), 46-49. https://journals.tnmu.uz/index.php/gtfj/article/view/592
BibTeX
@article{rakhimbaevagulnorasattarovna2024,
  title = {A SYSTEMATIC REVIEW EXAMINING THE APPLICATION OF STEM CELL–BASED THERAPY AS AN INNOVATIVE THERAPEUTIC INTERVENTION FOR PARKINSON'S DISEASE STM: PARKINSON KASALLIGINI DAVOLASHNING INNOVATSION U},
  author = {Rakhimbaeva, Gulnora Sattarovna and Musaeva , Yulduz Alpisovna and Akramova , Dilshoda Turdikulovna and Kasimova , Oksana Olegovna},
  journal = {Гуманитар ва табиий фанлар журнали},
  year = {2024},
  number = {13},
  pages = {46-49},
  url = {https://journals.tnmu.uz/index.php/gtfj/article/view/592}
}

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