Comparative assessment of the degree of harmful effects on experimental animals of the new osteoplastic material 47.5B and domestic bioactive glass BG-1D and assessment of its safety for use as an osteoplastic material. Material and methods: Three series of experiments were earned out and lethal doses were determined for the intraperitoneal and intragastric routes of administration of the drug to laboratory animals. Results: LD50 47.5B was 4274.51:4770.58 mg/kg when administered intragastrically and 2358.31:2895.65 mg/kg when administered intraperitoneally to rats. In animals that received bioactive glass BG-1D, this indicator changed slightly, amounting to 3439.04:3810.53 and 1732.77:2730.93 mg/kg, respectively. Conclusions: These materials can be attributed to practically non-toxic substances (according to the results of intraperitoneal administration of a suspension of substances to rats and mice) and to low-toxic substances (according to the results of intragastric M administration of a suspension of substances to rats).
| Mualliflar | Akbarov, A, Ziyadullaeva, N, Raxmanov, A, Axmedov, M, Акбаров, А, Зиядуллаева, Н, Рахманов, А, Ахмедов, М, Акбаров, А, Зиядуллаева, Н, Рахманов, А, Ахмедов, М |
|---|---|
| Jurnal | Stomatologiya |
| Nashr sanasi | 2021-03-26 |
| Son | 2 |
| Betlar | 8-10 |
| Til | O‘zbek |
| DOI | 10.34920/2091-5845-2021-36 |
DOI: 10.34920/2091-5845-2021-36 · Maqolaning asl sahifasi
остеопластический материал, полулетальная доза, острая токсичность, остеопластик хомашё, яримлетал доза, ўткир заҳарлик, osteoplastic material, median lethal dose, acute toxicity
To assess the clinical and hygienic state of the oral cavity in patients with HRAS of the oropharyngeal region with chronic cholecystitis. Material and methods: 96 patients with HRAS of the oropharyngeal region with…
Comparative study of the surface characteristics and the value of the untwisting torque of the dental implant “Iinplant.uz” subjected to sandblasting with 125 pmA12O3 particles, followed by immersion in a biomimetic…
To assess the effect of herpesvirus infection on the development and severity of the clinical course of recunent aphthous stomatitis of the oral cavity. Material and methods: The study included patients with chronic…
To study the quality of life in the pre-and postoperative period in patients with trigeminal neuralgia after microvascular decompression of the trigeminal nerve root. Material and methods: The results of observations of…
To improve the diagnosis of precancerous processes, as well as cancer of the oral mucosa using minimally invasive examination methods. Material and methods: On the basis of the Department of Hospital Therapeutic…
To study the dynamics of primary and general incidence of glaucoma among the adult population of Uzbekistan. Material and methods: To determine the level of glaucoma prevalence in the Republic of Uzbekistan and to…
To study the characteristic features of the cellular composition of blood in patients with acute purulent odontogenic ostitis of the jaw. Material and methods: The data obtained during the examination and treatment of…
1. Впервые проведенный в Республике Узбекистан анализ показал, что на 2019 год общая заболеваемость ВМД составляет 24,45, а первичная заболеваемость 8,38 на 100 тысяч взрослого населения, что превышает общемировые…
Objective: To study the characteristic features of local and systemic immunity in patients with acute purulent odontogemc ostitis of the jaw. Material and methods: The data obtained during the examination and treatment…
The aim of the study was to investigate the role of endoscopy in the diagnosis and treatment of chronic polypoid rhinosinusitis. We studied 125 patients with chronic polypoid rhinosinusitis, which held extensive…