Association of polymorphism RS1800497 gene of dopaminovega receptor of second type DRD2 with formation of attitude deficiency syndrome with hyperactivity in children

Saidkhodzhaeva, S, Karimov, Kh, Majidova, Y, Boboev, K, Саидходжаева, С, Каримов, Х, Маджидова, Ё, Бобоев, К, Саидходжаева, С, Каримов, Х, Маджидова, Ё, Бобоев, К

Nevrologiya · 2023-yil

Annotatsiya

The frequency distribution of alleles and genotypes of polymorphism RS1800497 of the DRD2 gene in the studied samples is statistically significantly different (χ2> 3.8; P <0.05), which indicates the presence of a pathogenetic connection between this genetic polymorphism and the formation of AdHd in children. Genotypes containing an unfavorable «T» allele (C / T and T / T or A1 / A2 and A1 / A1 genotypes, respectively) are independent genetic markers predicting an increased risk of developing AdHd in children. The genotype of C / C (A2 / A2) has a protective effect in the formation of the sign of the syndrome.

Maqola ma’lumotlari
MualliflarSaidkhodzhaeva, S, Karimov, Kh, Majidova, Y, Boboev, K, Саидходжаева, С, Каримов, Х, Маджидова, Ё, Бобоев, К, Саидходжаева, С, Каримов, Х, Маджидова, Ё, Бобоев, К
JurnalNevrologiya
Nashr sanasi2023-04-15
Jild1
Son4
Betlar13-16
TilRus

Kalit so‘zlar

синдром дефицита внимания, молекулярно-генетические механизмы, дети, attention deficit disorder, molecular genetic mechanisms, children, эътибор танқислиги синдроми, молекуляр-генетик механизмлар, болалар

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