Background. Atherosclerosis is a leading cause of cardiovascular mortality worldwide, significantly impacting public health. microRNA, as key regulators of gene expression, play a crucial role in the pathogenesis of atherosclerosis, offering novel avenues for diagnostics and therapeutics. Materials and methods. A review of contemporary literature was conducted to explore the link between non-coding molecules and atherosclerosis. Data from clinical studies identifying microRNA as potential biomarkers and therapeutic targets were included. Results.The findings demonstrate that microRNA influence critical stages of atherosclerosis pathogenesis, such as inflammation, apoptosis, and lipid metabolism. Their use as diagnostic biomarkers enhances the early detection of atherosclerosis, while their therapeutic potential presents new opportunities for treatment. Conclusion. MicroRNA represent a promising tool for managing cardiovascular diseases. Further research is necessary to develop effective diagnostic and therapeutic strategies.
| Mualliflar | Юсупалиева , Д, Низамов , У, Алиева , Р, Ахмедова, Ш, Шек , А, Yusupalieva , Dilnora, Nizamov , Ulugbek, Alieva , Rano, Akhmedova, Shokhista, Shek , Aleksandr, Yusupalieva , Dilnora, Nizamov , Ulugbek, Alieva , Rano, Akhmedova, Shokhista, Shek , Aleksandr |
|---|---|
| Jurnal | O‘zbekiston кardiologiyasi |
| Nashriyot | Ўзбекистон кардиологлар ассоциацияси |
| ISSN | 3060-4850 |
| Nashr sanasi | 2024-03-30 |
| Jild | 1 |
| Son | 1 |
| Betlar | 43-50 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| DOI | 10.70626/cardiouz-2024-1-00006 |
| Indeksga qo‘shilgan | 2026-08-26 |
DOI: 10.70626/cardiouz-2024-1-00006 · Maqolaning asl sahifasi
atherosclerosis, biomarkers, inflammation, microRNA, non-coding molecules, pathogenesis, therapeutic targets, aтеросклероз, биомаркеры, воспаление, микроРНК, некодирующие молекулы, терапевтические цели, kodlovchi bo‘lmagan molekulalar, Ateroskleroz, biomarkyerlar, mikroRNKlar, patogenez, terapevtik maqsadlar, yallig‘lanish
| APA | Юсупалиева , Д, Низамов , У, Алиева , Р, Ахмедова, Ш, Шек , А, Yusupalieva , Dilnora, Nizamov , Ulugbek, Alieva , Rano, Akhmedova, Shokhista, Shek , Aleksandr, Yusupalieva , Dilnora, Nizamov , Ulugbek, Alieva , Rano, Akhmedova, Shokhista, & Shek , Aleksandr (2024). The role of microRNA in the pathogenesis of atherosclerosis: new frontiers in research. O‘zbekiston кardiologiyasi, 1(1), 43-50. https://doi.org/10.70626/cardiouz-2024-1-00006 |
|---|---|
| GOST (OAK) | Юсупалиева , Д va b. The role of microRNA in the pathogenesis of atherosclerosis: new frontiers in research // O‘zbekiston кardiologiyasi. – 2024. – T. 1, № 1. – P. 43-50. – DOI: 10.70626/cardiouz-2024-1-00006. |
| MLA | Юсупалиева , Д, Низамов , У, Алиева , Р, Ахмедова, Ш, Шек , А, Yusupalieva , Dilnora, Nizamov , Ulugbek, Alieva , Rano, Akhmedova, Shokhista, Shek , Aleksandr, Yusupalieva , Dilnora, Nizamov , Ulugbek, Alieva , Rano, Akhmedova, Shokhista, and Shek , Aleksandr. “The role of microRNA in the pathogenesis of atherosclerosis: new frontiers in research.” O‘zbekiston кardiologiyasi, 1(1), 43-50, 2024. https://doi.org/10.70626/cardiouz-2024-1-00006 |
| Chicago | Юсупалиева , Д, Низамов , У, Алиева , Р, Ахмедова, Ш, Шек , А, Yusupalieva , Dilnora, Nizamov , Ulugbek, Alieva , Rano, Akhmedova, Shokhista, Shek , Aleksandr, Yusupalieva , Dilnora, Nizamov , Ulugbek, Alieva , Rano, Akhmedova, Shokhista, and Shek , Aleksandr. “The role of microRNA in the pathogenesis of atherosclerosis: new frontiers in research.” O‘zbekiston кardiologiyasi, 1(1), 43-50 (2024). https://doi.org/10.70626/cardiouz-2024-1-00006 |
| Harvard | Юсупалиева , Д, Низамов , У, Алиева , Р, Ахмедова, Ш, Шек , А, Yusupalieva , Dilnora, Nizamov , Ulugbek, Alieva , Rano, Akhmedova, Shokhista, Shek , Aleksandr, Yusupalieva , Dilnora, Nizamov , Ulugbek, Alieva , Rano, Akhmedova, Shokhista, and Shek , Aleksandr (2024) ‘The role of microRNA in the pathogenesis of atherosclerosis: new frontiers in research’, O‘zbekiston кardiologiyasi, 1(1), 43-50. https://doi.org/10.70626/cardiouz-2024-1-00006 |
| BibTeX | @article{article2024,
title = {The role of microRNA in the pathogenesis of atherosclerosis: new frontiers in research},
author = {Юсупалиева , Д and Низамов , У and Алиева , Р and Ахмедова, Ш and Шек , А and Yusupalieva , Dilnora and Nizamov , Ulugbek and Alieva , Rano and Akhmedova, Shokhista and Shek , Aleksandr and Yusupalieva , Dilnora and Nizamov , Ulugbek and Alieva , Rano and Akhmedova, Shokhista and Shek , Aleksandr},
journal = {O‘zbekiston кardiologiyasi},
year = {2024},
volume = {1},
number = {1},
pages = {43-50},
doi = {10.70626/cardiouz-2024-1-00006},
url = {https://doi.org/10.70626/cardiouz-2024-1-00006}
} |
Boshqa maqola uchun iqtibos tayyorlash
Background. To assess the frequency and characteristics of cardiac arrhythmias in relation to cardiac remodeling and blood prolactin levels in patients with peripartum cardiomyopathy (PPCM). Materials and methods. The…
Background. Contrast-induced nephropathy (CIN) is a common complication among patients with ischemic heart disease (IHD) undergoing percutaneous coronary intervention (PCI). Understanding the pathogenesis, risk factors…
Background. The 2023 ESC guidelines on cardiomyopathies introduce significant updates in diagnostic criteria, terminology, and treatment protocols. These guidelines aim to provide comprehensive approaches for diagnosis…
Background. This study explores the impact of anxiety and depressive disorders on the rehabilitation outcomes and long-term prognosis of patients with acute myocardial infarction (AMI) and unstable angina. The aim is to…
Arterial hypertension is a widely prevalent condition affecting millions of people worldwide. According to the World Health Organization (WHO) data, in 2021, more than 1 billion people suffered from hypertension. The…
Abstract. Contrast-induced nephropathy (CIN) represents a significant clinical challenge, particularly among patients diagnosed with coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM). The increased…
Background. Peripartum cardiomyopathy (PPCM) is a rare yet serious condition affecting women during late pregnancy or the postpartum period, often leading to complications such as ventricular arrhythmias and…
The leading cause of death worldwide is cardiovascular disease. In addition to the known factors leading to CVD, in recent years much attention has been paid to obesity as one of the components of cardiometabolic…
Background. The COVID-19 pandemic has posed significant health risks, particularly for elderly patients. Studies on the impact of COVID-19 in this age group have highlighted various atypical clinical manifestations…
O‘zbekiston кardiologiyasi — barcha maqolalar · 2024-yil arxivi
One of the most pressing issues in contemporary pediatrics and nephrology is chronic kidney disease (CKD), which is linked to early handicaps in patients as early as childhood, the emergence of chronic renal failure…
Scavenger receptor class B type 2 (CD36) is a multiligand transmembrane glycoprotein that combines the functions of a long-chain fatty acid transporter, an oxidised low-density lipoprotein receptor, a…
Comprehensive ultrasound navigation is an advanced approach that improves the accuracy and safety of brachial plexus block in regional anesthesia. This study included 150 patients with upper limb trauma and related…
Образования яичников у девочек различных возрастных групп представляют собой одну из актуальных проблем современной детской гинекологии. Своевременная и точная диагностика имеет решающее значение для сохранения…
Multiparametric ultrasound (MPUS) is a modern and safe method for evaluating skin structure in children. A total of 40 healthy children aged 3 months to 17 years were examined. High-resolution B-mode, Doppler imaging…
Comprehensive ultrasound examination is a highly informative, safe, and dynamic method for diagnosing adhesive small bowel obstruction (ASBO) in children. The study included 60 patients aged 1 month to 17 years. Key…
Настоящее исследование посвящено разработке алгоритма раннего выявления сенсоневральной тугоухости у детей с использованием методов полимеразной цепной реакции (ПЦР). Обследовано 235 детей с нарушениями слуха, из…
В статье представлены клинические аспекты и диагностические проблемы выявления сенсоневральной тугоухости у новорождённых с перинатальной патологией. Обследовано 115 новорождённых, из которых 35 перенесли асфиксию, а у…
Сенсоневральная тугоухость (СНТ) у детей остаётся одной из наиболее актуальных проблем современной оториноларингологии и медицинской генетики. Ранняя диагностика нарушений слуха играет ключевую роль в предупреждении…
Сенсоневральная тугоухость у новорождённых является одной из ведущих причин нарушения слухоречевого развития и ранней инвалидизации. Наиболее уязвимыми считаются дети, перенёсшие перинатальные осложнения, такие как…
Mazkur eksperimental tadqiqotda yuqori yog‘li ratsion va seftriaksonning lipid hamda uglevod almashinuviga alohida va birgalikdagi ta’siri 160 ta oq zotsiz erkak kalamushda o‘rganildi. Tajriba hayvonlari to‘rtta guruhga…
Мазкур тадқиқотда Тошкет вилоятидаги Ўрта Чирчиқ тумани 25-сонли, Бўка тумани 3-сонли ва 9-сонли давлат мактабгача таълим ташкилотларида 2025 йил ёз мавсумидаги таомномаларнинг озиқ-овқат маҳсулотлари билан…