Clinico-laboratorial part of the work is based on a survey of 96 patients with chronic generalized periodontitis (CGP). 22 people of the patients have chronic generalized periodontitis mild (HGPM), patients with chronic generalized periodontitis average degree (HGPA) and chronic generalized severe periodontitis (HGSP) 42 and 32 people respectively, combined with hypothyroidism. For objectification of the clinical research of the periodontal tissues, we used indicators such as the periodontal index, papillary-marginalalveolar index and the index of Ketze. For aexact determination of the intensity of the inflammatory processused Schiller-Pisarev trial. To measure the depth of periodontal pockets also held X-ray examinations. It was found that a significant activation of lipid peroxidation and reduced antioxidant defense observed in patients with severe CGP on the background of hypothyroidism. It is shown that thyroid dysfunction occurs pronounced activation of the immune system, manifested by increased levels of cytokines in the serum. The highest concentration of TNF, IL-1 and IL-4 were detected in patients with moderate CGP thyroid hypofunction.
| Mualliflar | Islamova , Nilufar, Сhakkonov , Fakhriddin, Исламова, Нилуфар, Чакконов, Фахриддин, Исламова , Нилуфар, Чаққонов , Фахриддин |
|---|---|
| Jurnal | Жамият ва инновациялар / Общество и инновации / Society and innovations |
| Nashr sanasi | 2020-10-10 |
| Jild | 1 |
| Son | 1/s |
| Betlar | 577-582 |
| Til | Rus |
| DOI | 10.47689/2181-1415-vol1-iss1/s-pp577-582 |
DOI: 10.47689/2181-1415-vol1-iss1/s-pp577-582 · Maqolaning asl sahifasi
продукты перекисного окисления, липиды, противовоспалительные цитокины, гипотиреоз, peroxidation products, lipids, anti-inflammatory cytokines, hypothyroidism, пероксидли оксидланиш маҳсулотлари, липидлар, яллиғланишга қарши ситокинлар, гипотиреоз
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