Changed levels of INTERLEUKIN-6 in parkinson's disease patients with COVID-19

MUMINOV Bekzod Askaroviv, MATMURODOV Rustambek Jumanazarovich, KHALIMOVA Khanifa Muxsinovna, NAZAROVA Madinabonu Faridovna, UMIROVA Surayyo Mamurjonovna

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2024-yil

Annotatsiya

The coronavirus disease (COVID-19) pandemic has attracted greater attention than ever before to the problems of immunopathology of human diseases, many of which are reflected in the study of neurodegenerative diseases. COVID-19 has clearly shown that one of the most significant targets of the RNA virus SARS-CoV-2 is the nervous system. Of particular interest is the relationship between COVID-19 and neurodegenerative diseases, including Parkinson's disease (PD). Parkinson's disease, according to its classical definition, is a chronic, progressive neurodegenerative disease. Currently, diagnosis is possible only with the development of motor symptoms (stiffness, oligo-, brady-, akinesia, rest tremor). The new coronavirus infection SARS-CoV-2 has neurotropic properties, and to date, cases of the development of delirium, meningitis, encephalitis, and acute transverse myelitis at the onset and/or against the background of the advanced course of COVID-19 have been described. Coronavirus can lead to an excessive, unregulated immune response in the host body - cytokine release syndrome. Increasingly, information is being heard that this type of immune response is an integral part of the development of target organ dysfunction and one of the main factors of morbidity. Immunological mechanisms in patients who have had Covid-19 have unique features. Uncontrolled production of cytokines by innate and acquired immune cells leads to the development of a “cytokine storm”. This work characterizes changes in the amount of immunological cytokines - interleukin-6 (IL-6) in Parkinson's disease. The impact of Covid-19 infection on the clinical course of Parkinson's disease, as well as the risk factor for the development of parkinsonism, is discussed.

Maqola ma’lumotlari
MualliflarMUMINOV Bekzod Askaroviv, MATMURODOV Rustambek Jumanazarovich, KHALIMOVA Khanifa Muxsinovna, NAZAROVA Madinabonu Faridovna, UMIROVA Surayyo Mamurjonovna
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2024-06-15
Jild9
Son2
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

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инфекция Covid-19, болезнь Паркинсона, “цитокиновый шторм”, интерлейкин-6, ферритин, Covid-19 infection, Parkinson's disease,, Covid-19 infeksiyasi, Parkinson kasalligi, “sitokinli shtorm”, interleykin-6, ferritin

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APAMUMINOV Bekzod Askaroviv, MATMURODOV Rustambek Jumanazarovich, KHALIMOVA Khanifa Muxsinovna, NAZAROVA Madinabonu Faridovna, & UMIROVA Surayyo Mamurjonovna (2024). CHANGED LEVELS OF INTERLEUKIN-6 IN PARKINSON'S DISEASE PATIENTS WITH COVID-19. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(2). https://tadqiqot.uz/index.php/biomedicine/article/view/9504
GOST (OAK)MUMINOV Bekzod Askaroviv va b. CHANGED LEVELS OF INTERLEUKIN-6 IN PARKINSON'S DISEASE PATIENTS WITH COVID-19 // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2024. – T. 9, № 2.
MLAMUMINOV Bekzod Askaroviv, MATMURODOV Rustambek Jumanazarovich, KHALIMOVA Khanifa Muxsinovna, NAZAROVA Madinabonu Faridovna, and UMIROVA Surayyo Mamurjonovna. “CHANGED LEVELS OF INTERLEUKIN-6 IN PARKINSON'S DISEASE PATIENTS WITH COVID-19.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(2), 2024. https://tadqiqot.uz/index.php/biomedicine/article/view/9504
ChicagoMUMINOV Bekzod Askaroviv, MATMURODOV Rustambek Jumanazarovich, KHALIMOVA Khanifa Muxsinovna, NAZAROVA Madinabonu Faridovna, and UMIROVA Surayyo Mamurjonovna. “CHANGED LEVELS OF INTERLEUKIN-6 IN PARKINSON'S DISEASE PATIENTS WITH COVID-19.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(2) (2024). https://tadqiqot.uz/index.php/biomedicine/article/view/9504
HarvardMUMINOV Bekzod Askaroviv, MATMURODOV Rustambek Jumanazarovich, KHALIMOVA Khanifa Muxsinovna, NAZAROVA Madinabonu Faridovna, and UMIROVA Surayyo Mamurjonovna (2024) ‘CHANGED LEVELS OF INTERLEUKIN-6 IN PARKINSON'S DISEASE PATIENTS WITH COVID-19’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(2). https://tadqiqot.uz/index.php/biomedicine/article/view/9504
BibTeX
@article{muminovbekzodaskaroviv2024,
  title = {CHANGED LEVELS OF INTERLEUKIN-6 IN PARKINSON'S DISEASE PATIENTS WITH COVID-19},
  author = {MUMINOV Bekzod Askaroviv and MATMURODOV Rustambek Jumanazarovich and KHALIMOVA Khanifa Muxsinovna and NAZAROVA Madinabonu Faridovna and UMIROVA Surayyo Mamurjonovna},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2024},
  volume = {9},
  number = {2},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/9504}
}

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