Morphological and immunohistochemical characteristics of lung tissue in newborns born to mothers infected with COVID-19

Karimov, Rasulbek, Tajibayeva, Ma’mura

Жанубий оролбўйи тиббиёт журнали · 2026-yil

Annotatsiya

Neonatal SARS-CoV-2 infeksiyasi kam uchrashi bilan birga, vertikal yoki perinatal yuqish holatlarida o‘pkada xarakterli morfologik va immunologik o‘zgarishlar namoyon bo‘lishi mumkin. Ushbu tadqiqotda COVID-19 musbat onalardan tug‘ilgan yangi tug‘ilgan chaqaloqlarning klinik ko‘rsatkichlari hamda autopsiya natijalari, gistopatologik, immunogistokimyoviy va o‘pka to‘qimalarining ultrastrukturaviy xususiyatlari asosida tahlil qilindi. Asosiy makroskopik va mikroskopik topilmalar qatorida diffuz alveolyar shikastlanish (DAL), II tip pnevmositlar giperplaziyasi, interstitsial mononuklear infiltratsiya, makrofaglarning to‘planishi va immun hujayra markerlarining (CD68, CD4, CD8, FOXP3, IL-6, IL-17) o‘zgaruvchan ifodasi qayd etildi. Shu bilan birga, joriy adabiyotdagi mavjud cheklovlar yoritilib, gistologik va immunogistokimyoviy o‘zgarishlarni aks ettiruvchi sxematik jadval taqdim etildi hamda kelgusida tizimli va keng qamrovli tadqiqotlar olib borish bo‘yicha tavsiyalar ishlab chiqildi.

Maqola ma’lumotlari
MualliflarKarimov, Rasulbek, Tajibayeva, Ma’mura
JurnalЖанубий оролбўйи тиббиёт журнали
NashriyotТТА Урганч филиали
ISSN3093-8740, 2012-2021
Nashr sanasi2026-02-02
Jild1
Son3
Betlar261-270
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

yangi tug‘ilgan chaqaloq, SARS-CoV-2, o‘pka patologiyasi, immunogistokimyo, alveolyar shikastlanish, II tip pnevmositlar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAKarimov, Rasulbek, & Tajibayeva, Ma’mura (2026). MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL CHARACTERISTICS OF LUNG TISSUE IN NEWBORNS BORN TO MOTHERS INFECTED WITH COVID-19. Жанубий оролбўйи тиббиёт журнали, 1(3), 261-270. http://journal.urdti.uz/index/article/view/42
GOST (OAK)Karimov, Rasulbek, Tajibayeva, Ma’mura MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL CHARACTERISTICS OF LUNG TISSUE IN NEWBORNS BORN TO MOTHERS INFECTED WITH COVID-19 // Жанубий оролбўйи тиббиёт журнали. – 2026. – T. 1, № 3. – P. 261-270.
MLAKarimov, Rasulbek, and Tajibayeva, Ma’mura. “MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL CHARACTERISTICS OF LUNG TISSUE IN NEWBORNS BORN TO MOTHERS INFECTED WITH COVID-19.” Жанубий оролбўйи тиббиёт журнали, 1(3), 261-270, 2026. http://journal.urdti.uz/index/article/view/42
ChicagoKarimov, Rasulbek, and Tajibayeva, Ma’mura. “MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL CHARACTERISTICS OF LUNG TISSUE IN NEWBORNS BORN TO MOTHERS INFECTED WITH COVID-19.” Жанубий оролбўйи тиббиёт журнали, 1(3), 261-270 (2026). http://journal.urdti.uz/index/article/view/42
HarvardKarimov, Rasulbek, and Tajibayeva, Ma’mura (2026) ‘MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL CHARACTERISTICS OF LUNG TISSUE IN NEWBORNS BORN TO MOTHERS INFECTED WITH COVID-19’, Жанубий оролбўйи тиббиёт журнали, 1(3), 261-270. http://journal.urdti.uz/index/article/view/42
BibTeX
@article{karimovrasulbek2026,
  title = {MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL CHARACTERISTICS OF LUNG TISSUE IN NEWBORNS BORN TO MOTHERS INFECTED WITH COVID-19},
  author = {Karimov, Rasulbek and Tajibayeva, Ma’mura},
  journal = {Жанубий оролбўйи тиббиёт журнали},
  year = {2026},
  volume = {1},
  number = {3},
  pages = {261-270},
  url = {http://journal.urdti.uz/index/article/view/42}
}

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