The authors studied the genetic marker C-174G of the IL-6 gene, the features of the distribution of the gene in functional constipation in children. The rarest genotype was homozygous for the C allele. In the group of healthy children, the C-genotype homozygous for the allele was more common than among patients. A positive association of the GG genotype (OR = 1.148) as well as the G allele (OR = 1.096) with functional constipation was shown. The presence of these allelic variants indicates an increased risk of developing functional constipation, the probability of a defect in the process of replacing guanine (G) with cytosine (C) is high.
| Mualliflar | Navruzova , Shakar, Xamrayeva , Dilnoza, Наврузова, Шакар, Хамраева , Дилноза, Navruzova , Shakar, Xamrayeva , Dilnoza |
|---|---|
| Jurnal | Халқаро илмий педиатрия журнали |
| Nashr sanasi | 2022-09-30 |
| Jild | 1 |
| Son | 5 |
| Betlar | 05-10 |
| Til | Rus |
| DOI | 10.56121/2181-2926-2022-5-05-10 |
DOI: 10.56121/2181-2926-2022-5-05-10 · Maqolaning asl sahifasi
дети,, ген, полиморфизм, запор, аллел, children, gene, polymorphism, constipation, allele, bola, gen, polimorfizm, qabziyat, allel
Small anomalies of the heart in children are anatomical changes in the architecture of the heart and trunk blood vessels that are not important, and in the functions of the cardiovascular system there are no sudden…
Clinical and hematological comparison of IDA in infants born to mothers with anemia. Under our supervision there were 195 children with iron deficiency anemia aged from 0 to 3 years. The age of the surveyed was: from 0…
In the patients examined by us, latent, subclinical and clinical forms of giardiasis were identified. In the latent form, the children did not complain. In the subclinical and clinical form, abdominal pain and dyspepsia…
In order to study the immune status in nephrotic syndrome in adolescent children with immunodiathesis, 120 children aged 7 to 11 years were examined. Of these: group 1 - 35 - NS (nephrotic form of CGN); 2-group -35 - NS…
The aim of the study was to study the possible pathogenetic mechanisms of the formation of bronchial hyperreactivity in bronchial asthma associated with microelementoses. The study group consisted of 45 children with…
Increasing the effectiveness of the treatment of dermatological patients is an important social task. This is due to the significant spread of a number of dermatoses and the severe course of some of them. The…
Acute infectious and inflammatory processes in the upper respiratory tract still form the main list of diseases in childhood, which maintains the constant interest in this pathology of specialists in various fields…
Review article. Collective data of modern literature data on the prevalence of iron deficiency conditions among adults and children, the importance of iron deficiency for the growth and development of children are…
This review presents information on the results of a scientific work devoted to the study of procalcitonin in premature babies. It has been established that non-infectious factors may also be the reason for the increase…
The immune status has been studied at 35 HIV-infected of children with ARS. The control group of comparison consisted from 14 practically healthy faces. At a HIV-infected of patients with ARS has revealed deep…