The authors studied the genetic marker C-174G of the IL-6 gene, the features of the distribution of the gene in functional constipation in children. The rarest genotype was homozygous for the C allele. In the group of healthy children, the C-genotype homozygous for the allele was more common than among patients. A positive association of the GG genotype (OR = 1.148) as well as the G allele (OR = 1.096) with functional constipation was shown. The presence of these allelic variants indicates an increased risk of developing functional constipation, the probability of a defect in the process of replacing guanine (G) with cytosine (C) is high.
| Mualliflar | Navruzova , Shakar, Xamrayeva , Dilnoza, Наврузова, Шакар, Хамраева , Дилноза, Navruzova , Shakar, Xamrayeva , Dilnoza |
|---|---|
| Jurnal | Халқаро илмий педиатрия журнали |
| Nashriyot | Андижон давлат тиббиёт институти; In Science МЧЖ |
| ISSN | 2181-2926, 2181-2926 |
| Nashr sanasi | 2022-09-30 |
| Jild | 1 |
| Son | 5 |
| Betlar | 05-10 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| DOI | 10.56121/2181-2926-2022-5-05-10 |
| Indeksga qo‘shilgan | 2026-08-26 |
DOI: 10.56121/2181-2926-2022-5-05-10 · Maqolaning asl sahifasi
дети,, ген, полиморфизм, запор, аллел, children, gene, polymorphism, constipation, allele, bola, gen, polimorfizm, qabziyat, allel
| APA | Navruzova , Shakar, Xamrayeva , Dilnoza, Наврузова, Шакар, Хамраева , Дилноза, Navruzova , Shakar, & Xamrayeva , Dilnoza (2022). INTERLEUKIN-6 GENE POLYMORPHISM IN FUNCTIONAL CONSTIPATION IN CHILDREN. Халқаро илмий педиатрия журнали, 1(5), 05-10. https://doi.org/10.56121/2181-2926-2022-5-05-10 |
|---|---|
| GOST (OAK) | Navruzova , Shakar va b. INTERLEUKIN-6 GENE POLYMORPHISM IN FUNCTIONAL CONSTIPATION IN CHILDREN // Халқаро илмий педиатрия журнали. – 2022. – T. 1, № 5. – P. 05-10. – DOI: 10.56121/2181-2926-2022-5-05-10. |
| MLA | Navruzova , Shakar, Xamrayeva , Dilnoza, Наврузова, Шакар, Хамраева , Дилноза, Navruzova , Shakar, and Xamrayeva , Dilnoza. “INTERLEUKIN-6 GENE POLYMORPHISM IN FUNCTIONAL CONSTIPATION IN CHILDREN.” Халқаро илмий педиатрия журнали, 1(5), 05-10, 2022. https://doi.org/10.56121/2181-2926-2022-5-05-10 |
| Chicago | Navruzova , Shakar, Xamrayeva , Dilnoza, Наврузова, Шакар, Хамраева , Дилноза, Navruzova , Shakar, and Xamrayeva , Dilnoza. “INTERLEUKIN-6 GENE POLYMORPHISM IN FUNCTIONAL CONSTIPATION IN CHILDREN.” Халқаро илмий педиатрия журнали, 1(5), 05-10 (2022). https://doi.org/10.56121/2181-2926-2022-5-05-10 |
| Harvard | Navruzova , Shakar, Xamrayeva , Dilnoza, Наврузова, Шакар, Хамраева , Дилноза, Navruzova , Shakar, and Xamrayeva , Dilnoza (2022) ‘INTERLEUKIN-6 GENE POLYMORPHISM IN FUNCTIONAL CONSTIPATION IN CHILDREN’, Халқаро илмий педиатрия журнали, 1(5), 05-10. https://doi.org/10.56121/2181-2926-2022-5-05-10 |
| BibTeX | @article{navruzovashakar2022,
title = {INTERLEUKIN-6 GENE POLYMORPHISM IN FUNCTIONAL CONSTIPATION IN CHILDREN},
author = {Navruzova , Shakar and Xamrayeva , Dilnoza and Наврузова, Шакар and Хамраева , Дилноза and Navruzova , Shakar and Xamrayeva , Dilnoza},
journal = {Халқаро илмий педиатрия журнали},
year = {2022},
volume = {1},
number = {5},
pages = {05-10},
doi = {10.56121/2181-2926-2022-5-05-10},
url = {https://doi.org/10.56121/2181-2926-2022-5-05-10}
} |
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