Myocardial conditioning is actually an important strategy in the management of ischemic reperfusion injury. The concept of postconditioning anesthetic is intriguing, its action occurs at a key moment (reperfusion, when ischemic reperfusion lesions are initiated), when activation of these cardioprotective mechanisms can overpower the mechanisms leading to ischemic reperfusion injuries. Desflurane and sevoflurane are volatile anesthetics often used during cardiac surgery. This review focuses on the efficacy of desflurane and sevoflurane administered during early reperfusion as a potential cardioprotective strategy. The mechanisms underlying the cardioprotective action of these agents and their ability to induce postconditioning have been discussed in detail, highlighting the role of reactive oxygen species generation, activation of cellular signaling pathways, and action on mitochondria. This may well be enough to revive the basis for the launch of the randomized clinical trials that are really needed to confirm that this strategy has real impact.
| Mualliflar | Ташкенбаева Элеонора Негматовна, Насырова Зарина Акбаровна, Саидов Максуд Арифович, Юсупова Мохинабону Фарруховна, Болтакулова Сарвиноз Дилшодовна |
|---|---|
| Jurnal | Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali |
| Nashriyot | Самарқанд давлат тиббиёт университети |
| Nashr sanasi | 2021-07-23 |
| Jild | 2 |
| Son | 2 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-26 |
десфлуран, севофлуран, реперфузия, посткондиционирование, прекондиционирование, реперфузионное повреждение, искусственное кровообращение, desflurane, sevoflurane, reperfusion, postconditioning, preconditioning, reperfusion injury, extracorporeal circulation, desfluran, sevofluran, reperfuziya, postkonditsionerlash, postkonditsionerlash, reperfuziya shikastlanishi, sun’iy qon aylanish
| APA | Ташкенбаева Элеонора Негматовна, Насырова Зарина Акбаровна, Саидов Максуд Арифович, Юсупова Мохинабону Фарруховна, & Болтакулова Сарвиноз Дилшодовна (2021). MECHANISMS OF CARDIOPROTECTIVE EFFECTS OF DESFLURANE AND SEVOFLURANE DURING REPERFUSION. Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali, 2(2). https://www.tadqiqot.uz/index.php/cardio/article/view/1912 |
|---|---|
| GOST (OAK) | Ташкенбаева Элеонора Негматовна va b. MECHANISMS OF CARDIOPROTECTIVE EFFECTS OF DESFLURANE AND SEVOFLURANE DURING REPERFUSION // Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali. – 2021. – T. 2, № 2. |
| MLA | Ташкенбаева Элеонора Негматовна, Насырова Зарина Акбаровна, Саидов Максуд Арифович, Юсупова Мохинабону Фарруховна, and Болтакулова Сарвиноз Дилшодовна. “MECHANISMS OF CARDIOPROTECTIVE EFFECTS OF DESFLURANE AND SEVOFLURANE DURING REPERFUSION.” Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali, 2(2), 2021. https://www.tadqiqot.uz/index.php/cardio/article/view/1912 |
| Chicago | Ташкенбаева Элеонора Негматовна, Насырова Зарина Акбаровна, Саидов Максуд Арифович, Юсупова Мохинабону Фарруховна, and Болтакулова Сарвиноз Дилшодовна. “MECHANISMS OF CARDIOPROTECTIVE EFFECTS OF DESFLURANE AND SEVOFLURANE DURING REPERFUSION.” Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali, 2(2) (2021). https://www.tadqiqot.uz/index.php/cardio/article/view/1912 |
| Harvard | Ташкенбаева Элеонора Негматовна, Насырова Зарина Акбаровна, Саидов Максуд Арифович, Юсупова Мохинабону Фарруховна, and Болтакулова Сарвиноз Дилшодовна (2021) ‘MECHANISMS OF CARDIOPROTECTIVE EFFECTS OF DESFLURANE AND SEVOFLURANE DURING REPERFUSION’, Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali, 2(2). https://www.tadqiqot.uz/index.php/cardio/article/view/1912 |
| BibTeX | @article{article2021,
title = {MECHANISMS OF CARDIOPROTECTIVE EFFECTS OF DESFLURANE AND SEVOFLURANE DURING REPERFUSION},
author = {Ташкенбаева Элеонора Негматовна and Насырова Зарина Акбаровна and Саидов Максуд Арифович and Юсупова Мохинабону Фарруховна and Болтакулова Сарвиноз Дилшодовна},
journal = {Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali},
year = {2021},
volume = {2},
number = {2},
url = {https://www.tadqiqot.uz/index.php/cardio/article/view/1912}
} |
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