Conventional anti-cancer therapy involves the use of chemical chemotherapeutics and radiation and are often non-specific in action. A major shortcoming in current treatment has been the development of drug resistance and inability to penetrate tumor cells. Alternative antitumor medicines with higher specificity and efficacy have therefore been explored. There is Significant interest in exploring the use of microbes as potential anticancer agents. We will introduce bacterial anti-cancer therapy with a focus on the various mechanisms involved in tumor targeting and suppression in this review. The bacteriotherapy in the design of novel treatments, approaches in combination with conventional cancer treatment may be effective in cancer therapies. We're focusing on the progress that has been made in the treatment of bacterial cancer. Patients in cancer treatment are attracted to tumor targeting peptides. These peptides are widely studied, delivering anticancer agents to tumor sites. In this study, we produced a new form of recombinant listeriolysin O (LLO) with genetically fused Anti HER2/neu peptide (AHNP) sequence adding to its C terminal end. The aim of the study was to engineer this pore forming toxin to make it much more specific to tumor cells. The results show that the LLO C terminal should not be changed, and it appears for the purpose of engineering and adding peptide modules, the N terminal of the toxin should be preferred. development of the small molecule that these constrained peptides provide drugs, but also provide insight into the atomic features of protein-protein interactions.
| Mualliflar | Mahmoud, Walaa Shakir |
|---|---|
| Jurnal | Innovative Multidisciplinary Journal of Applied Technology |
| Nashriyot | ТДТУ Қўқон филиали |
| ISSN | 2995-486X, 2995-486x |
| Nashr sanasi | 2024-05-17 |
| Jild | 2 |
| Son | 4 |
| Betlar | 173-180 |
| Til | Ingliz |
| Indeksga qo‘shilgan | 2026-08-26 |
Listeria, Listeriolysin, recombination
| APA | Mahmoud, Walaa Shakir (2024). Listeriolysin from Listeria and Their Effecting on AHNP. Innovative Multidisciplinary Journal of Applied Technology, 2(4), 173-180. https://www.multijournals.org/index.php/innovative/article/view/949 |
|---|---|
| GOST (OAK) | Mahmoud, Walaa Shakir Listeriolysin from Listeria and Their Effecting on AHNP // Innovative Multidisciplinary Journal of Applied Technology. – 2024. – T. 2, № 4. – P. 173-180. |
| MLA | Mahmoud, Walaa Shakir. “Listeriolysin from Listeria and Their Effecting on AHNP.” Innovative Multidisciplinary Journal of Applied Technology, 2(4), 173-180, 2024. https://www.multijournals.org/index.php/innovative/article/view/949 |
| Chicago | Mahmoud, Walaa Shakir. “Listeriolysin from Listeria and Their Effecting on AHNP.” Innovative Multidisciplinary Journal of Applied Technology, 2(4), 173-180 (2024). https://www.multijournals.org/index.php/innovative/article/view/949 |
| Harvard | Mahmoud, Walaa Shakir (2024) ‘Listeriolysin from Listeria and Their Effecting on AHNP’, Innovative Multidisciplinary Journal of Applied Technology, 2(4), 173-180. https://www.multijournals.org/index.php/innovative/article/view/949 |
| BibTeX | @article{mahmoudwalaashakir2024,
title = {Listeriolysin from Listeria and Their Effecting on AHNP},
author = {Mahmoud, Walaa Shakir},
journal = {Innovative Multidisciplinary Journal of Applied Technology},
year = {2024},
volume = {2},
number = {4},
pages = {173-180},
url = {https://www.multijournals.org/index.php/innovative/article/view/949}
} |
Boshqa maqola uchun iqtibos tayyorlash
the article studied the effectiveness of the drug Coraxan in the complex therapy of patients with coronary heart disease (CHD) and arterial hypertension (AH) in combination with chronic obstructive pulmonary disease…
This article is about professional development of practical psychologists and continuous professional development.
Chronic heart failure (CHF) is a major medical and social problem. The increase in morbidity is due to both an increase in the life expectancy of the population and the influence of risk factors that contribute to the…
In this study, cadmium ions were estimated in a new and simple way using green chemistry method, including the construction of an ion-selective electrode of nano-coated cadmium oxide (R-CdONPs) using Leucaena Leaves…
The most significant functions of the tax system, characterizing various aspects of its activities, include fiscal, social, regulatory, distribution, incentive and control. To implement the correct operation of each of…
Non-lactose-fermenting Escherichia coli (NLFEC) has a few descriptive studies restricted to infections in humans. Isolates of NLFEC characterised by their virulence ability, biofilm formation capacity and antimicrobial…
The enticement of rabbit meat stems mostly from a global trend: an increased interest in healthy eating. Rabbit meat, as a food product, aligns with the modern notion of a healthy lifestyle. Environmental problems…
This article presents an analysis of combined softeners of various structures and their technological work processes intended for basic and surface soil treatment. Combined softeners that are structurally similar to…
It is clear that corporate governance is the set of laws, customs, and procedures that regulate and control an organization. It covers how an organization's management, board of directors, shareholders, and other…
This article describes the pedagogical methods of using innovative technologies in teaching athletics in the process of teaching for university students of all directions, methods of teaching athletics, an example of…
Innovative Multidisciplinary Journal of Applied Technology — barcha maqolalar · 2024-yil arxivi
Non-lactose-fermenting Escherichia coli (NLFEC) has a few descriptive studies restricted to infections in humans. Isolates of NLFEC characterised by their virulence ability, biofilm formation capacity and antimicrobial…