Characteristics of the formation of the reproductive system in girls with congenital dysfunction of the adrenal cortex

Шопўлатов Эркин Холтожиевич, Эгамқулов Зайниддин Тошмухаммедович, Ганиев Фахриддин Истамқулович, Наил Салаватович Фатхулин, Шавкатов Ҳасан Шавкатович, Самадова Машхура Ёқубжон қизи

Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2026-yil

Annotatsiya

The aim of this study was to analyze the characteristics of the formation and functioning of the reproductive system in girls with congenital adrenal cortex dysfunction based on clinical, hormonal, and instrumental examination methods. The study was conducted between 2020 and 2026 in medical institutions of the Samarkand region and included a retrospective and prospective analysis of 20 patients under dynamic observation. The assessment comprised age and socio-demographic characteristics, general somatic status, anthropometric parameters, gynecological status, features of menstrual function, as well as the results of laboratory investigations (17-hydroxyprogesterone, testosterone, DHEA-S, cortisol) and ultrasound examination of the reproductive organs. The results demonstrated that the majority of girls with congenital adrenal cortex dysfunction exhibited clinical signs of hyperandrogenism, including acne, seborrhea, male-pattern hair growth, clitoromegaly, and insufficient development of the mammary glands. Menstrual cycle disorders were common, with opsomenorrhea and oligomenorrhea predominating, while amenorrhea and algodysmenorrhea were observed less frequently. Ultrasound findings revealed reduced uterine and ovarian sizes compared with age norms, and in some cases, polycystic ovarian changes. These findings confirm the significant negative impact of congenital adrenal cortex dysfunction on reproductive system development and emphasize the importance of early diagnosis and a comprehensive multidisciplinary approach to the management of affected patients

Maqola ma’lumotlari
MualliflarШопўлатов Эркин Холтожиевич, Эгамқулов Зайниддин Тошмухаммедович, Ганиев Фахриддин Истамқулович, Наил Салаватович Фатхулин, Шавкатов Ҳасан Шавкатович, Самадова Машхура Ёқубжон қизи
JurnalJournal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)
NashriyotСамарқанд давлат тиббиёт университети
ISSN2017-2021
Nashr sanasi2026-03-27
Jild7
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

врождённая дисфункция коры надпочечников, гиперандрогения, девочки, репродуктивная система, менструальный цикл, недостаточность 21-гидроксилазы., congenital adrenal cortex dysfunction, hyperandrogenism, girls, reproductive system, menstrual cycle, 21-hydroxylase deficiency., : buyrak usti bezi po‘stlog‘ining tug‘ma disfunktsiyasi, giperandrogeniya, qizlar, reproduktiv tizim, hayz sikli, 21-gidroksilaza yetishmovchiligi

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAШопўлатов Эркин Холтожиевич, Эгамқулов Зайниддин Тошмухаммедович, Ганиев Фахриддин Истамқулович, Наил Салаватович Фатхулин, Шавкатов Ҳасан Шавкатович, & Самадова Машхура Ёқубжон қизи (2026). CHARACTERISTICS OF THE FORMATION OF THE REPRODUCTIVE SYSTEM IN GIRLS WITH CONGENITAL DYSFUNCTION OF THE ADRENAL CORTEX. Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 7(1). https://tadqiqot.uz/index.php/uro/article/view/13337
GOST (OAK)Шопўлатов Эркин Холтожиевич va b. CHARACTERISTICS OF THE FORMATION OF THE REPRODUCTIVE SYSTEM IN GIRLS WITH CONGENITAL DYSFUNCTION OF THE ADRENAL CORTEX // Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали). – 2026. – T. 7, № 1.
MLAШопўлатов Эркин Холтожиевич, Эгамқулов Зайниддин Тошмухаммедович, Ганиев Фахриддин Истамқулович, Наил Салаватович Фатхулин, Шавкатов Ҳасан Шавкатович, and Самадова Машхура Ёқубжон қизи. “CHARACTERISTICS OF THE FORMATION OF THE REPRODUCTIVE SYSTEM IN GIRLS WITH CONGENITAL DYSFUNCTION OF THE ADRENAL CORTEX.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 7(1), 2026. https://tadqiqot.uz/index.php/uro/article/view/13337
ChicagoШопўлатов Эркин Холтожиевич, Эгамқулов Зайниддин Тошмухаммедович, Ганиев Фахриддин Истамқулович, Наил Салаватович Фатхулин, Шавкатов Ҳасан Шавкатович, and Самадова Машхура Ёқубжон қизи. “CHARACTERISTICS OF THE FORMATION OF THE REPRODUCTIVE SYSTEM IN GIRLS WITH CONGENITAL DYSFUNCTION OF THE ADRENAL CORTEX.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 7(1) (2026). https://tadqiqot.uz/index.php/uro/article/view/13337
HarvardШопўлатов Эркин Холтожиевич, Эгамқулов Зайниддин Тошмухаммедович, Ганиев Фахриддин Истамқулович, Наил Салаватович Фатхулин, Шавкатов Ҳасан Шавкатович, and Самадова Машхура Ёқубжон қизи (2026) ‘CHARACTERISTICS OF THE FORMATION OF THE REPRODUCTIVE SYSTEM IN GIRLS WITH CONGENITAL DYSFUNCTION OF THE ADRENAL CORTEX’, Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 7(1). https://tadqiqot.uz/index.php/uro/article/view/13337
BibTeX
@article{article2026,
  title = {CHARACTERISTICS OF THE FORMATION OF THE REPRODUCTIVE SYSTEM IN GIRLS WITH CONGENITAL DYSFUNCTION OF THE ADRENAL CORTEX},
  author = {Шопўлатов Эркин Холтожиевич and Эгамқулов Зайниддин Тошмухаммедович and Ганиев Фахриддин Истамқулович and Наил Салаватович Фатхулин and Шавкатов Ҳасан Шавкатович and Самадова Машхура Ёқубжон қизи},
  journal = {Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)},
  year = {2026},
  volume = {7},
  number = {1},
  url = {https://tadqiqot.uz/index.php/uro/article/view/13337}
}

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