Moderate vaginal dysbiosis is a shift in normal vaginal microbiota composition characterized by increased levels of opportunistic microbes and an ordinary high proportion of lactobacilli that make up 20 to 80 % of the total microbial population of the vagina. Some women with vaginal dysbiosis do not show any symptoms of the infectious inflammatory condition (IIC), which raises the question of whether their dysbiosis should be corrected. We studied the association between some parameters of the microbiota and clinical symptoms of IIC in female patients with moderate vaginal dysbiosis. Participants were distributed into two groups: group 1 included patients with clinical symptoms of IIC (n = 91), group 2 was comprised of asymptomatic patients (n = 44). Mean age was 26.9 ± 6.9 years. Vaginal microbial communities were studied using real-time polymerase chain reaction assays. Levels of six Lactobacillus species were measured in the vaginal discharge: Lactobacillus crispatus, L. iners, L. jensenii, L. gasseri, L. johnsonii, and L. vaginalis. We found that L. iners dominated the microbiota of 45 (49.5 %) symptomatic patients and only 9 (20.5 %) asymptomatic individuals (p = 0.002), unlike L. gasseri that significantly prevailed in the samples of asymptomatic patients: 23 (52.3 %) women vs 21 (23.1 %) in the group of patients with clinical signs of IIC (p = 0.001).
| Mualliflar | Шамсиева Малика Шухратовна, Негмаджанов Баходур Болтаевич, Насимоова Нигина Рустамовна, Жалолова Ирода Абдужабборовна |
|---|---|
| Jurnal | Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) |
| Nashr sanasi | 2023-05-20 |
| Jild | 4 |
| Son | 1 |
| Til | Rus |
микробиоценоз влагалища, вагинальные лактобациллы, Lactobacillus iners, Lactobacillus gasseri, умеренный дисбиоз влагалища, vaginal microbiota, vaginal lactobacilli, Lactobacillus iners, Lactobacillus gasseri, moderate vaginal dysbiosis, vaginal mikrobiotsenoz, vaginal laktobakteriyalar, Lactobacillus iners, Lactobacillus gasseri, mo
The medical history of 233 women with a diagnosis of miscarriage was analyzed. Fetal miscarriage was observed in term from 5 to 22 weeks. Patients underwent retrospective, cross-sectional cohort research, clinical and…
In recent years, there has been an increase in scientific interest in the problem that can be labeled "obesity and pregnancy". As a "prototype of the metabolic syndrome", pregnancy to some extent increases the risk of…
Over the past decade, the rate of caesarean section has increased by 25-30% worldwide. The increase in caesarean section requires the study of subsequent changes in the uterus. This article presents the current results…
According to WHO data, osteoporosis ranks fourth among non-communicable diseases as a cause of disability and mortality of patients from bone fractures (only 25% of patients are completely cured after hip fracture, 50%…
2019-2022 in the Regional Perinatal Center on the basis of the study. Pregnant women with 2 or more scars on the uterus after cesarean section were taken: Group I - with scars on the uterus after cesarean section - 30…
An analysis of the literature data showed a wide range of information about the frequency and structure of cervical pathology in the overall structure of gynecological morbidity among women in Uzbekistan. One of the…
Mayer-Rokitansky-Kyuster-Hauser, studied patients with ovarian polycystosis and metabolic syndrome in 2 groups in order to choose the most optimal type of treatment methods: 1 group – MRKXS, who had metabolic syndrome…
This article studies the prevalence of this disease, provides a brief review of the literature, analyzes the age composition and frequency of occurrence of certain forms of hypospadias, provides several types of…
Pregnant women with CGP and herpetic stomatitis were examined at various gestation periods. A low level of IL-10 in the oral fluid was revealed in pregnant women with herpetic stomatitis, more pronounced in the II…