Application of the FEMOFLOR-16 test to assess vaginal microbiocenosis in women with inflammatory diseases of the genital organs

Шамсиева Малика Шухратовна, Негмаджанов Баходур Болтаевич, Насимоова Нигина Рустамовна, Жалолова Ирода Абдужабборовна

Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2023-yil

Annotatsiya

Moderate vaginal dysbiosis is a shift in normal vaginal microbiota composition characterized by increased levels of opportunistic microbes and an ordinary high proportion of lactobacilli that make up 20 to 80 % of the total microbial population of the vagina. Some women with vaginal dysbiosis do not show any symptoms of the infectious inflammatory condition (IIC), which raises the question of whether their dysbiosis should be corrected. We studied the association between some parameters of the microbiota and clinical symptoms of IIC in female patients with moderate vaginal dysbiosis. Participants were distributed into two groups: group 1 included patients with clinical symptoms of IIC (n = 91), group 2 was comprised of asymptomatic patients (n = 44). Mean age was 26.9 ± 6.9 years. Vaginal microbial communities were studied using real-time polymerase chain reaction assays. Levels of six Lactobacillus species were measured in the vaginal discharge: Lactobacillus crispatus, L. iners, L. jensenii, L. gasseri, L. johnsonii, and L. vaginalis. We found that L. iners dominated the microbiota of 45 (49.5 %) symptomatic patients and only 9 (20.5 %) asymptomatic individuals (p = 0.002), unlike L. gasseri that significantly prevailed in the samples of asymptomatic patients: 23 (52.3 %) women vs 21 (23.1 %) in the group of patients with clinical signs of IIC (p = 0.001).

Maqola ma’lumotlari
MualliflarШамсиева Малика Шухратовна, Негмаджанов Баходур Болтаевич, Насимоова Нигина Рустамовна, Жалолова Ирода Абдужабборовна
JurnalJournal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)
NashriyotСамарқанд давлат тиббиёт университети
ISSN2017-2021
Nashr sanasi2023-05-20
Jild4
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

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микробиоценоз влагалища, вагинальные лактобациллы, Lactobacillus iners, Lactobacillus gasseri, умеренный дисбиоз влагалища, vaginal microbiota, vaginal lactobacilli, Lactobacillus iners, Lactobacillus gasseri, moderate vaginal dysbiosis, vaginal mikrobiotsenoz, vaginal laktobakteriyalar, Lactobacillus iners, Lactobacillus gasseri, mo

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APAШамсиева Малика Шухратовна, Негмаджанов Баходур Болтаевич, Насимоова Нигина Рустамовна, & Жалолова Ирода Абдужабборовна (2023). APPLICATION OF THE FEMOFLOR-16 TEST TO ASSESS VAGINAL MICROBIOCENOSIS IN WOMEN WITH INFLAMMATORY DISEASES OF THE GENITAL ORGANS. Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(1). https://tadqiqot.uz/index.php/uro/article/view/7228
GOST (OAK)Шамсиева Малика Шухратовна va b. APPLICATION OF THE FEMOFLOR-16 TEST TO ASSESS VAGINAL MICROBIOCENOSIS IN WOMEN WITH INFLAMMATORY DISEASES OF THE GENITAL ORGANS // Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали). – 2023. – T. 4, № 1.
MLAШамсиева Малика Шухратовна, Негмаджанов Баходур Болтаевич, Насимоова Нигина Рустамовна, and Жалолова Ирода Абдужабборовна. “APPLICATION OF THE FEMOFLOR-16 TEST TO ASSESS VAGINAL MICROBIOCENOSIS IN WOMEN WITH INFLAMMATORY DISEASES OF THE GENITAL ORGANS.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(1), 2023. https://tadqiqot.uz/index.php/uro/article/view/7228
ChicagoШамсиева Малика Шухратовна, Негмаджанов Баходур Болтаевич, Насимоова Нигина Рустамовна, and Жалолова Ирода Абдужабборовна. “APPLICATION OF THE FEMOFLOR-16 TEST TO ASSESS VAGINAL MICROBIOCENOSIS IN WOMEN WITH INFLAMMATORY DISEASES OF THE GENITAL ORGANS.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(1) (2023). https://tadqiqot.uz/index.php/uro/article/view/7228
HarvardШамсиева Малика Шухратовна, Негмаджанов Баходур Болтаевич, Насимоова Нигина Рустамовна, and Жалолова Ирода Абдужабборовна (2023) ‘APPLICATION OF THE FEMOFLOR-16 TEST TO ASSESS VAGINAL MICROBIOCENOSIS IN WOMEN WITH INFLAMMATORY DISEASES OF THE GENITAL ORGANS’, Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 4(1). https://tadqiqot.uz/index.php/uro/article/view/7228
BibTeX
@article{article2023,
  title = {APPLICATION OF THE FEMOFLOR-16 TEST TO ASSESS VAGINAL MICROBIOCENOSIS IN WOMEN WITH INFLAMMATORY DISEASES OF THE GENITAL ORGANS},
  author = {Шамсиева Малика Шухратовна and Негмаджанов Баходур Болтаевич and Насимоова Нигина Рустамовна and Жалолова Ирода Абдужабборовна},
  journal = {Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)},
  year = {2023},
  volume = {4},
  number = {1},
  url = {https://tadqiqot.uz/index.php/uro/article/view/7228}
}

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