Anti-Phospholipid Antibody Syndrome with Subdural Hematoma: A Case Report

MN Uddin, AKMB Karim, Nurunnahar Akter, Marwa Ahmed, M Orin, SA Tanni, M Asaduzzaman, MA Joarder, AJM Saleh, Syed Ahsan, SM Jahangir, MJ Chandy

PULSE · 2018-yil

Annotatsiya

A 33-year-old man with anti-phospholipid antibody syndrome associated with Budd Chiari syndrome and subdural hematoma. He developed venous thrombosis in his hepatic vein (stenting done) when laboratory studies demonstrated prolongation of activated partial thromboplastin time (APTT). Subdural hematoma demonstrated with Computed tomography (CT) of brain. Laboratory studies revealed thrombocytopenia, prolonged bleeding time and APTT, positive antinuclear antibody and positive test results for both lupus anticoagulant and an anti-cardiolipin antibody, namely antiphospholipid antibodies. Based on these findings, we consider that the tendency of this bleeding may have been due to antiphospholipid antibodies, attacking the platelet membranes and that the bridging veins in the subdural space may be the site at which the bleeding tendency easily appears. Antiphospholipid antibody syndrome accompanied by hemorrhagic complications had rarely been reported. We suggest that special attention should be given to hemorrhagic complications in patients with antiphospholipid antibody syndrome associated with fragility of the vessels and/or platelet dysfunction and on anticoagulant (warfarin).Pulse Vol.10 January-December 2017 p.25-28

Maqola ma’lumotlari
MualliflarMN Uddin, AKMB Karim, Nurunnahar Akter, Marwa Ahmed, M Orin, SA Tanni, M Asaduzzaman, MA Joarder, AJM Saleh, Syed Ahsan, SM Jahangir, MJ Chandy
JurnalPULSE
Nashr sanasi2018-10-19
Jild10
Son1
Betlar25-28
Tilen
DOI10.3329/pulse.v10i1.38608

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