Introduction: Extended spectrum ?-lactamases (ESBLs) are enzymes that mediate resistance to extended-spectrum (third generation) cephalosporins (e.g., ceftazidime, cefotaxime, and ceftriaxone) and monobactams (e.g., aztreonam) but do not affect cephamycins (e.g., cefoxitin and cefotetan) or carbapenems (e.g., meropenem or imipenem). Though the no. of ESBLs producing organism has been increasing day by day, the detection methods and treatment option for them are extremely limited.Aims & Objective: The present study was undertaken to investigate the rate of ESBLs production and their antibiotic susceptibility pattern.Materials & Method: A total 110 Gram negative isolates from various clinical samples from a tertiary care hospital were studied and ESBLs production was detected by double disc synergy test. Antibiotic susceptibility test was done for commonly used antibiotics.Results: Among the total isolates 66.36% (73) were ESBLs producer, and the rate of ESBLs positivity was 80.32% for E.coli (49 out of 61), 25% for Pseudomonas spp (6 out of 24), 71.42% for Klebsiella spp (10 out of 14), 80% for Enterobacter spp (4 out of 5), 100% for Acinetobacter spp (4 out of 4) and 0% for Proteus spp (0 out of 2). ESBLs producing organisms were resistant to most of the antibiotics but 100% were sensitive to imepenem.Conclusion: Screening for ESBLs production needs to be carried out routinely in every clinical diagnostic laboratory to guide clinicians in proper selection of antibiotics.Pulse Vol.8 January-December 2015 p.15-20
| Mualliflar | Suma Mita Biswas, Nikhat Ara, Nasreen Huda, Sofia Andalib, Mohammad Hefzur Rahman, Md Ruhul Amin Miah |
|---|---|
| Jurnal | PULSE |
| Nashr sanasi | 2016-06-06 |
| Jild | 8 |
| Son | 1 |
| Betlar | 15-20 |
| Til | en |
| DOI | 10.3329/pulse.v8i1.28096 |
DOI: 10.3329/pulse.v8i1.28096 · Maqolaning asl sahifasi · PDF
Aim: Nontuberculous mycobacterium (NTM) causes many types of infections including respiratory and non-respiratory infections such as skin and soft tissue infections, lymphadenitis, meningitis, gastro-intestinal…
Aim and Objective: Dysembryoplastic neuroepithelial tumour is an unusual brain tumour with varied incidence commonly occured in younger age group. We report a 16-year old female diagnosed as a case of dysembryoplastic…
Acute stroke is an infrequent disease of pediatric age group patients. MoyaMoya is a rare cerebro vascular disease of unknown etiology. We report a case of 14-year-old male child who presented with right-sided…
There are controversies about the management of the PCL injuries among the Orthopaedic surgeons. We present our result of 14 cases that underwent surgical management for the avulsion fracture of the tibial insertion of…
Background: Most diabetic patients have silent ischemia and cardiac dysfunction that is usually observed in the late phase of the disease when it becomes clinically obvious. We hypothesized that left ventricular…
Large left to right shunt across an atrial septal defect results in volume overload and dilatation of the right atrium and ventricle. As a result of increased flow into the lungs, the pulmonary arteries, capillaries &…
Background: Central aortic pressure has often been shown to be more closely associated with markers of vascular function and incidence of cardiovascular events compared to peripheral pressure. However, the potential…
Transfusion transmitted infection (TTIs) is still a concern associated with blood transfusion as hepatitis B and hepatitis C remains a major public health problem in a country like Bangladesh. The trends of the…
Purpose: Although moderate- to high-intensity statin therapy is increasingly recommended in cardiovascular disease patients, the efficacy and safety in elderly patients have not been proven clearly. Here, we compare the…
Abstract not available DOI: http://dx.doi.org/10.3329/pulse.v5i2.20263 Pulse Vol.5 July 2011 p.31-40