Detection and Antimicrobial Susceptibility Pattern of Extended Spectrum Beta Lactamases (ESBLs) Producing Gram Negative Bacteria from Different Clinical Samples

Suma Mita Biswas, Nikhat Ara, Nasreen Huda, Sofia Andalib, Mohammad Hefzur Rahman, Md Ruhul Amin Miah

PULSE · 2016-yil

Annotatsiya

Introduction: Extended spectrum ?-lactamases (ESBLs) are enzymes that mediate resistance to extended-spectrum (third generation) cephalosporins (e.g., ceftazidime, cefotaxime, and ceftriaxone) and monobactams (e.g., aztreonam) but do not affect cephamycins (e.g., cefoxitin and cefotetan) or carbapenems (e.g., meropenem or imipenem). Though the no. of ESBLs producing organism has been increasing day by day, the detection methods and treatment option for them are extremely limited.Aims & Objective: The present study was undertaken to investigate the rate of ESBLs production and their antibiotic susceptibility pattern.Materials & Method: A total 110 Gram negative isolates from various clinical samples from a tertiary care hospital were studied and ESBLs production was detected by double disc synergy test. Antibiotic susceptibility test was done for commonly used antibiotics.Results: Among the total isolates 66.36% (73) were ESBLs producer, and the rate of ESBLs positivity was 80.32% for E.coli (49 out of 61), 25% for Pseudomonas spp (6 out of 24), 71.42% for Klebsiella spp (10 out of 14), 80% for Enterobacter spp (4 out of 5), 100% for Acinetobacter spp (4 out of 4) and 0% for Proteus spp (0 out of 2). ESBLs producing organisms were resistant to most of the antibiotics but 100% were sensitive to imepenem.Conclusion: Screening for ESBLs production needs to be carried out routinely in every clinical diagnostic laboratory to guide clinicians in proper selection of antibiotics.Pulse Vol.8 January-December 2015 p.15-20

Maqola ma’lumotlari
MualliflarSuma Mita Biswas, Nikhat Ara, Nasreen Huda, Sofia Andalib, Mohammad Hefzur Rahman, Md Ruhul Amin Miah
JurnalPULSE
NashriyotPROFI университетининг
ISSN2074-1855, 2235-8668
Nashr sanasi2016-06-06
Jild8
Son1
Betlar15-20
TilIngliz
Ilmiy sohaPsixologiya
DOI10.3329/pulse.v8i1.28096
Indeksga qo‘shilgan2026-09-02

DOI: 10.3329/pulse.v8i1.28096 · Maqolaning asl sahifasi · PDF

Ilmiy soha

Psixologiya

Iqtibos keltirish

APASuma Mita Biswas, Nikhat Ara, Nasreen Huda, Sofia Andalib, Mohammad Hefzur Rahman, & Md Ruhul Amin Miah (2016). Detection and Antimicrobial Susceptibility Pattern of Extended Spectrum Beta Lactamases (ESBLs) Producing Gram Negative Bacteria from Different Clinical Samples. PULSE, 8(1), 15-20. https://doi.org/10.3329/pulse.v8i1.28096
GOST (OAK)Suma Mita Biswas va b. Detection and Antimicrobial Susceptibility Pattern of Extended Spectrum Beta Lactamases (ESBLs) Producing Gram Negative Bacteria from Different Clinical Samples // PULSE. – 2016. – T. 8, № 1. – P. 15-20. – DOI: 10.3329/pulse.v8i1.28096.
MLASuma Mita Biswas, Nikhat Ara, Nasreen Huda, Sofia Andalib, Mohammad Hefzur Rahman, and Md Ruhul Amin Miah. “Detection and Antimicrobial Susceptibility Pattern of Extended Spectrum Beta Lactamases (ESBLs) Producing Gram Negative Bacteria from Different Clinical Samples.” PULSE, 8(1), 15-20, 2016. https://doi.org/10.3329/pulse.v8i1.28096
ChicagoSuma Mita Biswas, Nikhat Ara, Nasreen Huda, Sofia Andalib, Mohammad Hefzur Rahman, and Md Ruhul Amin Miah. “Detection and Antimicrobial Susceptibility Pattern of Extended Spectrum Beta Lactamases (ESBLs) Producing Gram Negative Bacteria from Different Clinical Samples.” PULSE, 8(1), 15-20 (2016). https://doi.org/10.3329/pulse.v8i1.28096
HarvardSuma Mita Biswas, Nikhat Ara, Nasreen Huda, Sofia Andalib, Mohammad Hefzur Rahman, and Md Ruhul Amin Miah (2016) ‘Detection and Antimicrobial Susceptibility Pattern of Extended Spectrum Beta Lactamases (ESBLs) Producing Gram Negative Bacteria from Different Clinical Samples’, PULSE, 8(1), 15-20. https://doi.org/10.3329/pulse.v8i1.28096
BibTeX
@article{sumamitabiswas2016,
  title = {Detection and Antimicrobial Susceptibility Pattern of Extended Spectrum Beta Lactamases (ESBLs) Producing Gram Negative Bacteria from Different Clinical Samples},
  author = {Suma Mita Biswas and Nikhat Ara and Nasreen Huda and Sofia Andalib and Mohammad Hefzur Rahman and Md Ruhul Amin Miah},
  journal = {PULSE},
  year = {2016},
  volume = {8},
  number = {1},
  pages = {15-20},
  doi = {10.3329/pulse.v8i1.28096},
  url = {https://doi.org/10.3329/pulse.v8i1.28096}
}

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