Associations between Type 2 Diabetes Mellitus and Arterial Stiffness: A Prospective Analysis Based on the Maine-Syracuse Study

Merrill F. Elias, Georgina E. Crichton, Peter J. Dearborn, Michael A. Robbins, Walter P. Abhayaratna

PULSE · 2017-yil

Annotatsiya

Background: The aim of this study was to investigate prospective associations between type 2 diabetes mellitus status and the gold standard non-invasive method for ascertaining arterial stiffness, carotid femoral pulse wave velocity. Methods: The prospective analysis employed 508 community-dwelling participants (mean age 61 years, 60% women) from the Maine-Syracuse Longitudinal Study. Pulse wave velocity at wave 7 (2006-2010) was compared between those with type 2 diabetes mellitus at wave 6 (2001-2006) (n = 52) and non-diabetics at wave 6 (n = 456), with adjustment for demographic factors, cardiovascular risk factors and lifestyle- and pulse wave velocity-related factors. Results: Type 2 diabetes mellitus status was associated with a significantly higher pulse wave velocity (12.5 ± 0.36 vs. 10.4 ± 0.12 m/s). Multivariate adjustment for other cardiovascular risk factors and lifestyle- and pulse wave velocity-related variables did not attenuate the findings. The risk of an elevated pulse wave velocity (≥12 m/s) was over 9 times higher for those with uncontrolled type 2 diabetes mellitus than for those without diabetes (OR 9.14, 95% CI 3.23-25.9, p < 0.001). Conclusions: Type 2 diabetes mellitus, particularly if uncontrolled, is significantly associated with risk of arterial stiffness later in life. Effective management of diabetes mellitus is an important element of protection from arterial stiffness.

Maqola ma’lumotlari
MualliflarMerrill F. Elias, Georgina E. Crichton, Peter J. Dearborn, Michael A. Robbins, Walter P. Abhayaratna
JurnalPULSE
NashriyotPROFI университетининг
ISSN2074-1855, 2235-8668
Nashr sanasi2017-01-01
Jild5
Son1-4
Betlar88-98
TilIngliz
Ilmiy sohaPsixologiya
DOI10.1159/000479560
Indeksga qo‘shilgan2026-09-02

DOI: 10.1159/000479560 · Maqolaning asl sahifasi

Ilmiy soha

Psixologiya

Iqtibos keltirish

APAMerrill F. Elias, Georgina E. Crichton, Peter J. Dearborn, Michael A. Robbins, & Walter P. Abhayaratna (2017). Associations between Type 2 Diabetes Mellitus and Arterial Stiffness: A Prospective Analysis Based on the Maine-Syracuse Study. PULSE, 5(1-4), 88-98. https://doi.org/10.1159/000479560
GOST (OAK)Merrill F. Elias va b. Associations between Type 2 Diabetes Mellitus and Arterial Stiffness: A Prospective Analysis Based on the Maine-Syracuse Study // PULSE. – 2017. – T. 5, № 1-4. – P. 88-98. – DOI: 10.1159/000479560.
MLAMerrill F. Elias, Georgina E. Crichton, Peter J. Dearborn, Michael A. Robbins, and Walter P. Abhayaratna. “Associations between Type 2 Diabetes Mellitus and Arterial Stiffness: A Prospective Analysis Based on the Maine-Syracuse Study.” PULSE, 5(1-4), 88-98, 2017. https://doi.org/10.1159/000479560
ChicagoMerrill F. Elias, Georgina E. Crichton, Peter J. Dearborn, Michael A. Robbins, and Walter P. Abhayaratna. “Associations between Type 2 Diabetes Mellitus and Arterial Stiffness: A Prospective Analysis Based on the Maine-Syracuse Study.” PULSE, 5(1-4), 88-98 (2017). https://doi.org/10.1159/000479560
HarvardMerrill F. Elias, Georgina E. Crichton, Peter J. Dearborn, Michael A. Robbins, and Walter P. Abhayaratna (2017) ‘Associations between Type 2 Diabetes Mellitus and Arterial Stiffness: A Prospective Analysis Based on the Maine-Syracuse Study’, PULSE, 5(1-4), 88-98. https://doi.org/10.1159/000479560
BibTeX
@article{merrillfelias2017,
  title = {Associations between Type 2 Diabetes Mellitus and Arterial Stiffness: A Prospective Analysis Based on the Maine-Syracuse Study},
  author = {Merrill F. Elias and Georgina E. Crichton and Peter J. Dearborn and Michael A. Robbins and Walter P. Abhayaratna},
  journal = {PULSE},
  year = {2017},
  volume = {5},
  number = {1-4},
  pages = {88-98},
  doi = {10.1159/000479560},
  url = {https://doi.org/10.1159/000479560}
}

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