RADIOPAQUE ACTIVITY OF IODINE CONTAINING METHYLENE-BIS-CARBAMATE

Kimyo va kimyo texnologiyasi · 2020-yil

Annotatsiya

Considering that many derivatives of bis carbamates have different biological activity, it was intuitive to produce a targeted synthesis of new derivatives of bis carbamates by the interaction of hexamethylene diisocyanate with 3,5-diode-4-hydroxybenzoic acid and 2,4,6-triiodophenol (1: 2 mol, respectively) in freshly distilled dry pyridine at 95-110 оC for 6 hours, the corresponding derivatives were obtained - methylene bis carbamates. Experimental studies have been conducted to identify the acute toxicity and radiopaque properties of the synthesized new N, -hexamethylene bis (2,6-diode-4-carboxyphenylcarbamate).

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JurnalKimyo va kimyo texnologiyasi
Nashr sanasi2020-03-20
Betlar32-37
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DOI10.51348/khpt2980

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