New tetracyclic THIENO[3,2-d]PYRIMIDINE scaffold derivatives synthesized and aminated

A. Buronov, Azizbek Nasrullaev, Khurshed Bozorov, N. Lifei, Haji Akber Aisa

Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi · 2025-yil

Annotatsiya

The synthesis of novel thieno[3,2-d]pyrimidine derivatives started with the reaction of 5-bromo-2 chlorobenzonitrile with ethyl-2-mercaptoacetate to give the compound AT-2. The addition of lactames to the formed AT-2 followed by cyclization gave the compound AR-05. The amination reaction was then used to facilitate the formation of a C-C bond. The intermediate AR-05 was formed under a base in dioxane in the presence of aromatic amines and a palladium catalyst, forming a new nitrogen-carbon bond. AR-58-1 and AR-82 were synthesized as end products. The structure of the new compounds was studied by analyzing the results obtained by studying their physical and physico-chemical properties.

Maqola ma’lumotlari
MualliflarA. Buronov, Azizbek Nasrullaev, Khurshed Bozorov, N. Lifei, Haji Akber Aisa
JurnalSamarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi
NashriyotСамарқанд давлат университети
ISSN2091-5446, 2181-1296
Nashr sanasi2025-03-29
Jild1
Son1
Betlar12-17
TilIngliz
Ilmiy sohaKimyo
DOI10.59251/2181-1296.2025.v1.149.2.3208
Indeksga qo‘shilgan2026-09-02

DOI: 10.59251/2181-1296.2025.v1.149.2.3208 · Maqolaning asl sahifasi

Ilmiy soha

Kimyo

Iqtibos keltirish

APAA. Buronov, Azizbek Nasrullaev, Khurshed Bozorov, N. Lifei, & Haji Akber Aisa (2025). NEW TETRACYCLIC THIENO[3,2-d]PYRIMIDINE SCAFFOLD DERIVATIVES SYNTHESIZED AND AMINATED. Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(1), 12-17. https://doi.org/10.59251/2181-1296.2025.v1.149.2.3208
GOST (OAK)A. Buronov va b. NEW TETRACYCLIC THIENO[3,2-d]PYRIMIDINE SCAFFOLD DERIVATIVES SYNTHESIZED AND AMINATED // Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi. – 2025. – T. 1, № 1. – P. 12-17. – DOI: 10.59251/2181-1296.2025.v1.149.2.3208.
MLAA. Buronov, Azizbek Nasrullaev, Khurshed Bozorov, N. Lifei, and Haji Akber Aisa. “NEW TETRACYCLIC THIENO[3,2-d]PYRIMIDINE SCAFFOLD DERIVATIVES SYNTHESIZED AND AMINATED.” Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(1), 12-17, 2025. https://doi.org/10.59251/2181-1296.2025.v1.149.2.3208
ChicagoA. Buronov, Azizbek Nasrullaev, Khurshed Bozorov, N. Lifei, and Haji Akber Aisa. “NEW TETRACYCLIC THIENO[3,2-d]PYRIMIDINE SCAFFOLD DERIVATIVES SYNTHESIZED AND AMINATED.” Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(1), 12-17 (2025). https://doi.org/10.59251/2181-1296.2025.v1.149.2.3208
HarvardA. Buronov, Azizbek Nasrullaev, Khurshed Bozorov, N. Lifei, and Haji Akber Aisa (2025) ‘NEW TETRACYCLIC THIENO[3,2-d]PYRIMIDINE SCAFFOLD DERIVATIVES SYNTHESIZED AND AMINATED’, Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(1), 12-17. https://doi.org/10.59251/2181-1296.2025.v1.149.2.3208
BibTeX
@article{aburonov2025,
  title = {NEW TETRACYCLIC THIENO[3,2-d]PYRIMIDINE SCAFFOLD DERIVATIVES SYNTHESIZED AND AMINATED},
  author = {A. Buronov and Azizbek Nasrullaev and Khurshed Bozorov and N. Lifei and Haji Akber Aisa},
  journal = {Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi},
  year = {2025},
  volume = {1},
  number = {1},
  pages = {12-17},
  doi = {10.59251/2181-1296.2025.v1.149.2.3208},
  url = {https://doi.org/10.59251/2181-1296.2025.v1.149.2.3208}
}

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