Norlabdane Compounds Containing Thiosemicarbazone or 1,3-Thiazole Fragments: Synthesis and Antimicrobial Activity

Svetlana Blaja, Lidia Lungu, K. I. Kuchkova, Alexandru Ciocârlan, Alic Barbă, Nicoleta Vornicu, Aculina Arîcu

Химия природных соединений · 2021-yil

Annotatsiya

New di-, tri-, tetra-, and pentanorlabdane compounds with thiosemicarbazone and 1,3-thiazole fragments were synthesized. Their antifungal and antibacterial activities were studied. The main advantages of this research were the available starting material, i.e., the natural labdane diterpenoid (–)-sclareol, which was isolated from renewable resources, and the high probability of biological activity combined with the low toxicity of these compounds because of their natural origin.

DOI: 10.1007/s10600-021-03292-3 · Maqolaning asl sahifasi

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