Optimization of anti-edema therapy in severe traumatic brain injury

Ashurov T.Kh

Klinik fanlar yilnomasi · 2025-yil

Annotatsiya

Neuroinflammation and cerebral edema are central mechanisms in the pathophysiology of severe traumatic brain injury (TBI). This study evaluated the effectiveness of adding Paracetamol infusion to standard therapy in patients with severe TBI. A total of 40 patients were enrolled, divided into control and main groups. In the main group, significant reductions in pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) and an increase in the anti-inflammatory cytokine IL-10 were observed, alongside improvements in Glasgow Coma Scale scores and reduced cerebral edema volume on CT scans. The multimodal approach incorporating Paracetamol infusion demonstrated promising potential for controlling neuroinflammation and accelerating recovery in severe TBI patients.

Maqola ma’lumotlari
MualliflarAshurov T.Kh
JurnalKlinik fanlar yilnomasi
NashriyotБухоро давлат тиббиёт институти
ISSN2025-2026, 0009-0006
Nashr sanasi2025-08-12
Jild2
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

traumatic brain injury, neuroinflammation, cerebral edema, paracetamol, Glasgow coma scale, intracranial hypertension, черепно-мозговая травма, нейровоспаление, отек мозга, Парацетамол, шкала комы Глазго, внутричерепная гипертензия, bosh miya jarohati, neyron yallig’lanishi, miya shishi, paratsetamol, Glazgo koma shkalasi, intrakranial gipertenziya

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAAshurov T.Kh (2025). OPTIMIZATION OF ANTI-EDEMA THERAPY IN SEVERE TRAUMATIC BRAIN INJURY. Klinik fanlar yilnomasi, 2(1). https://tadqiqot.uz/index.php/spjacd/article/view/12069
GOST (OAK)Ashurov T.Kh OPTIMIZATION OF ANTI-EDEMA THERAPY IN SEVERE TRAUMATIC BRAIN INJURY // Klinik fanlar yilnomasi. – 2025. – T. 2, № 1.
MLAAshurov T.Kh. “OPTIMIZATION OF ANTI-EDEMA THERAPY IN SEVERE TRAUMATIC BRAIN INJURY.” Klinik fanlar yilnomasi, 2(1), 2025. https://tadqiqot.uz/index.php/spjacd/article/view/12069
ChicagoAshurov T.Kh. “OPTIMIZATION OF ANTI-EDEMA THERAPY IN SEVERE TRAUMATIC BRAIN INJURY.” Klinik fanlar yilnomasi, 2(1) (2025). https://tadqiqot.uz/index.php/spjacd/article/view/12069
HarvardAshurov T.Kh (2025) ‘OPTIMIZATION OF ANTI-EDEMA THERAPY IN SEVERE TRAUMATIC BRAIN INJURY’, Klinik fanlar yilnomasi, 2(1). https://tadqiqot.uz/index.php/spjacd/article/view/12069
BibTeX
@article{ashurovtkh2025,
  title = {OPTIMIZATION OF ANTI-EDEMA THERAPY IN SEVERE TRAUMATIC BRAIN INJURY},
  author = {Ashurov T.Kh},
  journal = {Klinik fanlar yilnomasi},
  year = {2025},
  volume = {2},
  number = {1},
  url = {https://tadqiqot.uz/index.php/spjacd/article/view/12069}
}

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