Leukoencephalopathy is a severe pathology characterised by damage to the white matter of the central nervous system, which often develops in children with acute lymphoblastic leukaemia (ALL) and in the course of its treatment. The risk of leukoencephalopathy in patients with ALL is associated with cytostatic chemotherapy, especially with such drugs as methotrexate. Early detection and effective treatment of this complication are of great importance for improving outcomes, minimising neurological disorders and maintaining the quality of life of children. The article analyses the pathogenesis, clinical manifestations, diagnostic methods and preventive measures of leukoencephalopathy. The importance of an individual approach and interdisciplinary management is also emphasised in this case.
| Mualliflar | Gulyamova Durdona Nasriddinovna, Abduraxmonova Nigora, Matyakubova Xonzoda Bekturdiyevna, Гулямова Дурдона Насриддиновна, Абдурахмонова Нигора, Матякубова Хонзода Бектурдиевна, Gulyamova Durdona Nasriddinovna, Abduraxmonova Nigora, Matyakubova Xonzoda Bekturdiyevna |
|---|---|
| Jurnal | Research Focus |
| Nashriyot | Ветеринария ИТИ ва “Илм-фан ва инновациялар академияси” МЧЖ |
| ISSN | 2181-3833 |
| Nashr sanasi | 2025-05-05 |
| Jild | 4 |
| Son | 4 |
| Betlar | 276-277 |
| Til | Ingliz |
| Ilmiy soha | Veterinariya |
| DOI | 10.66073/researchfocus.v4i4.1593 |
| Indeksga qo‘shilgan | 2026-09-12 |
DOI: 10.66073/researchfocus.v4i4.1593 · Maqolaning asl sahifasi
лейкоэнцефалопатия, острый лимфобластный лейкоз (ОЛЛ), детская онкология, нейротоксичность, осложнения химиотерапии, метотрексат, диагностика, профилактика, центральная нервная система, leukoencephalopathy, acute lymphoblastic leukaemia (ALL), paediatric oncology, neurotoxicity, complications of chemotherapy, methotrexate, diagnosis, prevention, central nervous system, leykoensefalopatiya, o'tkir limfoblastik leykoz (OLL), bolalar onkologiyasi, neyrotoksiklik, kimyoterapiya asoratlari, metotreksat, tashxis, profilaktika, markaziy asab tizimi
| APA | Gulyamova Durdona Nasriddinovna, Abduraxmonova Nigora, Matyakubova Xonzoda Bekturdiyevna, Гулямова Дурдона Насриддиновна, Абдурахмонова Нигора, Матякубова Хонзода Бектурдиевна, Gulyamova Durdona Nasriddinovna, Abduraxmonova Nigora, & Matyakubova Xonzoda Bekturdiyevna (2025). LEUKOENCEPHALOPATHY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL).. Research Focus, 4(4), 276-277. https://doi.org/10.66073/researchfocus.v4i4.1593 |
|---|---|
| GOST (OAK) | Gulyamova Durdona Nasriddinovna va b. LEUKOENCEPHALOPATHY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL). // Research Focus. – 2025. – T. 4, № 4. – P. 276-277. – DOI: 10.66073/researchfocus.v4i4.1593. |
| MLA | Gulyamova Durdona Nasriddinovna, Abduraxmonova Nigora, Matyakubova Xonzoda Bekturdiyevna, Гулямова Дурдона Насриддиновна, Абдурахмонова Нигора, Матякубова Хонзода Бектурдиевна, Gulyamova Durdona Nasriddinovna, Abduraxmonova Nigora, and Matyakubova Xonzoda Bekturdiyevna. “LEUKOENCEPHALOPATHY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)..” Research Focus, 4(4), 276-277, 2025. https://doi.org/10.66073/researchfocus.v4i4.1593 |
| Chicago | Gulyamova Durdona Nasriddinovna, Abduraxmonova Nigora, Matyakubova Xonzoda Bekturdiyevna, Гулямова Дурдона Насриддиновна, Абдурахмонова Нигора, Матякубова Хонзода Бектурдиевна, Gulyamova Durdona Nasriddinovna, Abduraxmonova Nigora, and Matyakubova Xonzoda Bekturdiyevna. “LEUKOENCEPHALOPATHY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)..” Research Focus, 4(4), 276-277 (2025). https://doi.org/10.66073/researchfocus.v4i4.1593 |
| Harvard | Gulyamova Durdona Nasriddinovna, Abduraxmonova Nigora, Matyakubova Xonzoda Bekturdiyevna, Гулямова Дурдона Насриддиновна, Абдурахмонова Нигора, Матякубова Хонзода Бектурдиевна, Gulyamova Durdona Nasriddinovna, Abduraxmonova Nigora, and Matyakubova Xonzoda Bekturdiyevna (2025) ‘LEUKOENCEPHALOPATHY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL).’, Research Focus, 4(4), 276-277. https://doi.org/10.66073/researchfocus.v4i4.1593 |
| BibTeX | @article{gulyamovadurdonanasriddinovna2025,
title = {LEUKOENCEPHALOPATHY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL).},
author = {Gulyamova Durdona Nasriddinovna and Abduraxmonova Nigora and Matyakubova Xonzoda Bekturdiyevna and Гулямова Дурдона Насриддиновна and Абдурахмонова Нигора and Матякубова Хонзода Бектурдиевна and Gulyamova Durdona Nasriddinovna and Abduraxmonova Nigora and Matyakubova Xonzoda Bekturdiyevna},
journal = {Research Focus},
year = {2025},
volume = {4},
number = {4},
pages = {276-277},
doi = {10.66073/researchfocus.v4i4.1593},
url = {https://doi.org/10.66073/researchfocus.v4i4.1593}
} |
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