Objective of the study. To study treatment adherence and factors associated with it in patients with chronic heart failure (CHF). Material and Methods. Patients with verified CHF were selected for the study. A total of 72 patients, in whom the diagnosis of CHF was clarified at inclusion, were included. 40 patients were previously observed, 32 patients applied for the first time. During the inclusion visit and after 1 year the general adherence to drug therapy was determined using the NSEP Adherence Scale questionnaire, and the adherence to drugs with proven influence on the prognosis of the disease was studied in this cohort of patients. Adherence was assessed in points: 0 points - absolute adherence; 1-2 points - partial, incomplete adherence; 3 points - partial nonadherence; 4 points - absolute nonadherence. Patients who scored 0 points on the questionnaire were considered committed; patients who scored 1 point or more were considered noncommitted. Results. At inclusion in the study 47% of patients were absolutely committed to the previously prescribed drug therapy, 43% - partially committed and partially non-adherent, 10% - absolutely non-adherent. Among the main factors of non-adherence to drug therapy 38% of patients noted a large number of prescribed drugs, 27% - forgot to take prescribed drugs; fear of side effects as a reason for non-adherence to therapy was noted by 22% of patients. After 1 year of follow-up the change of nonadherence factors was noted. The main place was taken by forgetfulness (40%), the second most frequent factor was a large number of drugs (27%), fear of side effects was noted by only 13% of patients, which is significantly less than during the inclusion visit. The number of patients who were reluctant to take multiple medications decreased from 5 to 1 (21 and 5%, respectively). After 1 year of follow-up, the forgetfulness factor continued to be the leading factor, and the number of patients who did not want to take medications with proven efficacy in CHF decreased significantly (from 15% to 5%). Conclusions. Factors of non-adherence to drug therapy in patients with CHF are diverse and further study and correction are required. The registry study allows to identify factors more characteristic for real clinical practice. This study shows for the first time the factors of non-adherence to specific medications in patients with CHS.
| Mualliflar | Madaminov A.M., Shoalimova Z.M., Shukurdjanova S.M. |
|---|---|
| Jurnal | Ёш олимлар тиббиёт журнали |
| Nashr sanasi | 2025-03-05 |
| Son | 13 |
| Betlar | 48-53 |
| Til | Rus |
adherence to treatment, nonadherence factors, chronic heart failure.
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