Evaluation of ursodeoxycholic acid effectiveness in metabolic syndrome treatment

Avazova T.A.

Гуманитар ва табиий фанлар журнали · 2025-yil

Annotatsiya

Metabolic syndrome is a multifactorial condition characterized by obesity, insulin resistance, dyslipidemia, and hypertension, which significantly increase the risk of cardiovascular disease and type 2 diabetes mellitus. The global prevalence of metabolic syndrome has been steadily rising, making it an urgent public health concern that requires effective therapeutic strategies. Traditional management mainly focuses on lifestyle modifications and pharmacological interventions aimed at individual components of the syndrome. Ursodeoxycholic Acid (UDCA), a hydrophilic bile acid widely used for cholestatic liver diseases, has recently attracted scientific attention for its potential metabolic effects. Experimental and clinical studies suggest that UDCA may improve insulin sensitivity, reduce oxidative stress, and enhance lipid metabolism, in addition to exerting hepatoprotective actions. These properties make UDCA a promising candidate for addressing the complex pathophysiology of metabolic syndrome. This article evaluates the effectiveness of UDCA in the management of metabolic syndrome by analyzing clinical outcomes such as weight reduction, liver enzyme normalization, lipid profile improvements, and decreased insulin resistance. The findings demonstrate that UDCA can serve as a valuable adjunctive treatment, especially in patients with concomitant liver dysfunction and metabolic risk factors.

Maqola ma’lumotlari
MualliflarAvazova T.A.
JurnalГуманитар ва табиий фанлар журнали
NashriyotEMU University
ISSN2026-2027, 2181-4007
Nashr sanasi2025-12-10
Son28
Betlar52-57
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

Ursodeoxycholic acid, Metabolic syndrome, Insulin resistance, Lipid profile, Liver function, Hepatoprotection, Oxidative stress.

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAAvazova T.A. (2025). EVALUATION OF URSODEOXYCHOLIC ACID EFFECTIVENESS IN METABOLIC SYNDROME TREATMENT. Гуманитар ва табиий фанлар журнали, (28), 52-57. https://journals.tnmu.uz/index.php/gtfj/article/view/3016
GOST (OAK)Avazova T.A. EVALUATION OF URSODEOXYCHOLIC ACID EFFECTIVENESS IN METABOLIC SYNDROME TREATMENT // Гуманитар ва табиий фанлар журнали. – 2025. – № 28. – P. 52-57.
MLAAvazova T.A. “EVALUATION OF URSODEOXYCHOLIC ACID EFFECTIVENESS IN METABOLIC SYNDROME TREATMENT.” Гуманитар ва табиий фанлар журнали, (28), 52-57, 2025. https://journals.tnmu.uz/index.php/gtfj/article/view/3016
ChicagoAvazova T.A. “EVALUATION OF URSODEOXYCHOLIC ACID EFFECTIVENESS IN METABOLIC SYNDROME TREATMENT.” Гуманитар ва табиий фанлар журнали, (28), 52-57 (2025). https://journals.tnmu.uz/index.php/gtfj/article/view/3016
HarvardAvazova T.A (2025) ‘EVALUATION OF URSODEOXYCHOLIC ACID EFFECTIVENESS IN METABOLIC SYNDROME TREATMENT’, Гуманитар ва табиий фанлар журнали, (28), 52-57. https://journals.tnmu.uz/index.php/gtfj/article/view/3016
BibTeX
@article{avazovata2025,
  title = {EVALUATION OF URSODEOXYCHOLIC ACID EFFECTIVENESS IN METABOLIC SYNDROME TREATMENT},
  author = {Avazova T.A.},
  journal = {Гуманитар ва табиий фанлар журнали},
  year = {2025},
  number = {28},
  pages = {52-57},
  url = {https://journals.tnmu.uz/index.php/gtfj/article/view/3016}
}

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