Morphological and morphometric evaluation of structural changes in the stomach of experimental animals with induced colitis

Sanoyev B.A., Hamroyev B.B.

Гуманитар ва табиий фанлар журнали · 2025-yil

Annotatsiya

This scientific study investigates the morphological and morphometric alterations in the gastric mucosa under experimental ulcerative colitis (UC) conditions. An ulcerative colitis model was induced in laboratory rats using dextran sulfate sodium (DSS). Gastric tissue samples were collected and examined using standard histological techniques. Morphological analysis revealed erosions, glandular atrophy, inflammatory infiltration, and signs of epithelial regeneration in the gastric mucosa. Morphometric evaluation included measurements of mucosal thickness, glandular density, crypt depth, and the nucleus-to-cytoplasm ratio. Statistically significant differences were observed between the UC group and the control group, indicating that ulcerative colitis induces systemic effects not limited to the colon, but also involving upper gastrointestinal organs such as the stomach. The proposed method of combined morphological and morphometric assessment may serve as a reliable approach for better understanding the pathogenesis and early diagnosis of ulcerative colitis.

Maqola ma’lumotlari
MualliflarSanoyev B.A., Hamroyev B.B.
JurnalГуманитар ва табиий фанлар журнали
NashriyotEMU University
ISSN2026-2027, 2181-4007
Nashr sanasi2025-10-05
Son26
Betlar109-113
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

ulcerative colitis, gastric mucosa, DSS model, morphological changes, morphometry, laboratory experiment, inflammation

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APASanoyev B.A., Hamroyev B.B. (2025). MORPHOLOGICAL AND MORPHOMETRIC EVALUATION OF STRUCTURAL CHANGES IN THE STOMACH OF EXPERIMENTAL ANIMALS WITH INDUCED COLITIS. Гуманитар ва табиий фанлар журнали, (26), 109-113. https://journals.tnmu.uz/index.php/gtfj/article/view/2404
GOST (OAK)Sanoyev B.A., Hamroyev B.B. MORPHOLOGICAL AND MORPHOMETRIC EVALUATION OF STRUCTURAL CHANGES IN THE STOMACH OF EXPERIMENTAL ANIMALS WITH INDUCED COLITIS // Гуманитар ва табиий фанлар журнали. – 2025. – № 26. – P. 109-113.
MLASanoyev B.A., Hamroyev B.B. “MORPHOLOGICAL AND MORPHOMETRIC EVALUATION OF STRUCTURAL CHANGES IN THE STOMACH OF EXPERIMENTAL ANIMALS WITH INDUCED COLITIS.” Гуманитар ва табиий фанлар журнали, (26), 109-113, 2025. https://journals.tnmu.uz/index.php/gtfj/article/view/2404
ChicagoSanoyev B.A., Hamroyev B.B. “MORPHOLOGICAL AND MORPHOMETRIC EVALUATION OF STRUCTURAL CHANGES IN THE STOMACH OF EXPERIMENTAL ANIMALS WITH INDUCED COLITIS.” Гуманитар ва табиий фанлар журнали, (26), 109-113 (2025). https://journals.tnmu.uz/index.php/gtfj/article/view/2404
HarvardSanoyev B.A., Hamroyev B.B (2025) ‘MORPHOLOGICAL AND MORPHOMETRIC EVALUATION OF STRUCTURAL CHANGES IN THE STOMACH OF EXPERIMENTAL ANIMALS WITH INDUCED COLITIS’, Гуманитар ва табиий фанлар журнали, (26), 109-113. https://journals.tnmu.uz/index.php/gtfj/article/view/2404
BibTeX
@article{sanoyevbahamroyevbb2025,
  title = {MORPHOLOGICAL AND MORPHOMETRIC EVALUATION OF STRUCTURAL CHANGES IN THE STOMACH OF EXPERIMENTAL ANIMALS WITH INDUCED COLITIS},
  author = {Sanoyev B.A., Hamroyev B.B.},
  journal = {Гуманитар ва табиий фанлар журнали},
  year = {2025},
  number = {26},
  pages = {109-113},
  url = {https://journals.tnmu.uz/index.php/gtfj/article/view/2404}
}

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