Effectiveness of polyoxidonium application in the treatment of obstructive bronchitis in children

Abduvokhidova A.A., Shavazi N.M.

Гуманитар ва табиий фанлар журнали · 2025-yil

Annotatsiya

Obstructive bronchitis is a common cause of hospitalization of children, characterized by bronchoobstructive syndrome and respiratory failure. The main etiologic factor is viral infection. Considering the key role of bronchial inflammation and reduced immunity in the pathogenesis of the disease, we conducted therapy with the immunomodulator Polioxidonium. The study involved 54 children aged from six months to five years who underwent inpatient treatment in pediatrics departments #1 and #2 of the Samarkand branch of the Republican Scientific Center for Emergency Medical Care. The patients were divided into two groups. In the second group, Polyoxidonium was added to the standard therapy and administered intramuscularly at a dosage of 0.1 mg/kg every other day. The results showed that patients who received Polioxidonium had statistically significant acceleration of cyanosis regression (by 0.7 days; P<0.05), cough cessation (by 0.9 days; P<0.05), disappearance of respiratory failure signs (by 0.7 days; P<0.05) and dyspnea (by 1.4 days; P<0.001) compared to the control group. Consequently, the use of Polioxidonium resulted in a reduction in the average duration of hospitalization by 1.1 bed-days (P<0.01) compared with conventional treatment.

Maqola ma’lumotlari
MualliflarAbduvokhidova A.A., Shavazi N.M.
JurnalГуманитар ва табиий фанлар журнали
NashriyotEMU University
ISSN2026-2027, 2181-4007
Nashr sanasi2025-07-05
Son23
Betlar332-334
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

children, Polyoxidonium, treatment, obstructive bronchitis.

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAAbduvokhidova A.A., Shavazi N.M. (2025). EFFECTIVENESS OF POLYOXIDONIUM APPLICATION IN THE TREATMENT OF OBSTRUCTIVE BRONCHITIS IN CHILDREN. Гуманитар ва табиий фанлар журнали, (23), 332-334. https://journals.tnmu.uz/index.php/gtfj/article/view/2098
GOST (OAK)Abduvokhidova A.A., Shavazi N.M. EFFECTIVENESS OF POLYOXIDONIUM APPLICATION IN THE TREATMENT OF OBSTRUCTIVE BRONCHITIS IN CHILDREN // Гуманитар ва табиий фанлар журнали. – 2025. – № 23. – P. 332-334.
MLAAbduvokhidova A.A., Shavazi N.M. “EFFECTIVENESS OF POLYOXIDONIUM APPLICATION IN THE TREATMENT OF OBSTRUCTIVE BRONCHITIS IN CHILDREN.” Гуманитар ва табиий фанлар журнали, (23), 332-334, 2025. https://journals.tnmu.uz/index.php/gtfj/article/view/2098
ChicagoAbduvokhidova A.A., Shavazi N.M. “EFFECTIVENESS OF POLYOXIDONIUM APPLICATION IN THE TREATMENT OF OBSTRUCTIVE BRONCHITIS IN CHILDREN.” Гуманитар ва табиий фанлар журнали, (23), 332-334 (2025). https://journals.tnmu.uz/index.php/gtfj/article/view/2098
HarvardAbduvokhidova A.A., Shavazi N.M (2025) ‘EFFECTIVENESS OF POLYOXIDONIUM APPLICATION IN THE TREATMENT OF OBSTRUCTIVE BRONCHITIS IN CHILDREN’, Гуманитар ва табиий фанлар журнали, (23), 332-334. https://journals.tnmu.uz/index.php/gtfj/article/view/2098
BibTeX
@article{abduvokhidovaaashavazinm2025,
  title = {EFFECTIVENESS OF POLYOXIDONIUM APPLICATION IN THE TREATMENT OF OBSTRUCTIVE BRONCHITIS IN CHILDREN},
  author = {Abduvokhidova A.A., Shavazi N.M.},
  journal = {Гуманитар ва табиий фанлар журнали},
  year = {2025},
  number = {23},
  pages = {332-334},
  url = {https://journals.tnmu.uz/index.php/gtfj/article/view/2098}
}

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